Halogenation Reaction of S-Aryl-S-[(1,2-benzisoxazol-3-yl) methyl] sulfoximide
スポンサーリンク
概要
- 論文の詳細を見る
The reactions of the title free sulfoximide with N-bromosuccinimide (NBS) and N-chlorosuccinimide (NCS) afforded the corresponding α-halogenated"free"sulfoximides in good yields. The α-bromination proceeded via a facile N-bromination followed by a bromine transfer reaction of the resulting N-bromosulfoximide. The NCS chlorination, in contrast, proceeded via direct α-chlorination, not via N-chlorination. However, in the presence of potassium carbonate or silica gel N-chlorination occurred predominantly in the NCS chlorination.
- 公益社団法人日本薬学会の論文
- 1982-04-25
著者
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西村 温樹
Research Laboratories:dainippon Pharmaceutical Co. Ltd.
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西村 温樹
Research Laboratories Dainippon Pharmaceutical Co. Ltd.
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宇野 準
Research Laboratories, Dainippon Pharmaceutical Co., Ltd.,
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成戸 俊介
Research Laboratories Dainippon Pharmaceutical Co. Ltd
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成戸 俊介
Exploratory Research Laboratories Dainippon Pharmaceutical Co. Ltd.
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宇野 準
大日本製薬株式会社総合研究所
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吉田 豊吉
Research Laboratories, Dainippon Pharmaceutical Co., Ltd.
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宇野 準
大日本製薬株式会社
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宇野 準
大日本製薬
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宇野 準
Research Laboratory Dainippon Pharmaceutical Co. Ltd.
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宇野 準
Research Laboratories Dainippon Pharmaceutical Co. Ltd.
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吉田 豊吉
Exploratory Research Laboratories Dainippon Pharmaceutical Co. Ltd.
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