Syntheses of New Thiamine Derivatives
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概要
- 論文の詳細を見る
Oxidation of thiamine sodium salt (I) with iodine in the presence of amines (II) gave S-aminothiamines (III). When III was treated with weak acids, oxathiolane derivative (VIII) was obtained. From VIII, some new thiamine derivatives, pyrimido [4,5-c] [1,2,6]-10H-thiadiazocine (XIII), S-phosphate (XVI) derivatives and so forth, were derived. An analogue of XVI, cyclic O, S-phosphate (XVIII) was also synthesized.
- 公益社団法人日本薬学会の論文
- 1971-04-25
著者
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中野 純次
Research Laboratories, Dainippon Pharmaceutical Co., Ltd.,
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西村 温樹
Research Laboratories:dainippon Pharmaceutical Co. Ltd.
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西村 温樹
Research Laboratories Dainippon Pharmaceutical Co. Ltd.
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中野 純次
Research Laboratories Dainippon Pharmaceutical Co. Ltd.
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