Mannich Reaction of Dihydropyridine Derivatives. II. Reaction with Primary Amines
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概要
- 論文の詳細を見る
Dialkyl 4-aryl-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylates (I) were subjected to the Mannich reaction with excess paraformaldehyde and primary amine in ethanolic solution. Novel ring-system compounds, dialkyl t-6-aryl-1H, 6H-2,3,6a, 7,8,9-hexahydro-2,3a, 8-triazaphenalene-5,γ-6a-dicarboxylate derivatives (III), and some intermediary products were obtained stereoselectively. The reaction pathway and the stereochemistry of these products are discussed.
- 公益社団法人日本薬学会の論文
- 1981-05-23
著者
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西村 温樹
Research Laboratories:dainippon Pharmaceutical Co. Ltd.
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西村 温樹
Research Laboratories Dainippon Pharmaceutical Co. Ltd.
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有富 治郎
Research Laboratories, Dainippon Pharmaceutical Co., Ltd.
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有富 治郎
Research Laboratories Dainippon Pharmaceutical Co. Ltd.
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