Synthesis and Antiucler Activity of the Metabolites of 2-(4-Ethyl-1-piperazinyl)-4-phenylquinoline Dimaleate(AS-2646), a Novel Gastric Antisecretory and Antiulcer Agent
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概要
- 論文の詳細を見る
The metabolites 3 and 4 of 2-(4-ethyl-1-piperazinyl)-4-phenylquinoline dimaleate (AS-2646,1), a candidate as a gastric antisecretory and antiulcer drug, were synthesized to confirm thr proposed structures. The effects of the metabolites 2-4 on ulcer induced by stress were determined.
- 公益社団法人日本薬学会の論文
- 1989-01-25
著者
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岡 真
大日本製薬
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松本 純一
Exploratory Research Laboratories, Dainippon Pharmaceutical Co., Ltd.,
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松本 純一
Exploratory Research Laboratories Dainippon Pharmaceutical Company Ltd.
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松本 純一
Research Laboratories Dainippon Pharmaceutical Co. Ltd.
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日野 克彦
Research Laboratories, Dainippon Pharmaceutical Co., Ltd.,
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宇野 準
Research Laboratories, Dainippon Pharmaceutical Co., Ltd.,
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岡 眞
Research Laboratories Dainippon Pharmaceutical Co. Ltd.
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宇野 準
大日本製薬株式会社総合研究所
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河島 勝良
Research Laboratories, Dainippon Pharmaceutical Co., Ltd.,
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日野 克彦
Research Laboratories Dainippon Pharmaceutical Co. Ltd.
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宇野 準
大日本製薬株式会社
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宇野 準
大日本製薬
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宇野 準
Research Laboratory Dainippon Pharmaceutical Co. Ltd.
-
松本 純一
Exploratory Research Laboratories Dainippon Pharmaceutical Co. Ltd.
-
河島 勝良
Research Laboratories Dainippon Pharmaceutical Co. Ltd.
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宇野 準
Research Laboratories Dainippon Pharmaceutical Co. Ltd.
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