Synthesis and Spasmolytic Activity of Aminoalkyl 2-Substituted-2-(1,2-benzisoxazol-3-yl)acetates(Medicinal Chemistry,Chemical)
スポンサーリンク
概要
- 論文の詳細を見る
Several aminoalkyl esters of 2-(1,2-benzisoxazol-3-yl)-2-cyclohexylacetic acid, 1-(1,2-benzisoxazol-3-yl)-1-cyclopentanecarboxylic acid, and 1-(1,2-benzisoxazol-3-yl)-1-cyclohexanecarboxylic acid and their quaternary ammonium salts were synthesized. The anticholinergic (anti-Aeh) and musculotropic (anti-KCl) activities of these compounds were examined. Among them, 3-(N,N-diethylamino)-propyl 2-(1,2-benzisoxazol-3-yl)-2-cyclohexylacetate (8b) showed potent anti-Ach and anti-KCl activities.
- 公益社団法人日本薬学会の論文
- 1987-05-25
著者
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成戸 俊介
Research Laboratories Dainippon Pharmaceutical Co. Ltd
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成戸 俊介
Exploratory Research Laboratories Dainippon Pharmaceutical Co. Ltd.
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Naruto Shunsuke
Research Laboratories Dainippon Parmaceutical Co. Ltd.
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水田 泰之
Research Laboratories, Dainippon Pharmaceutical Co., Ltd,
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Naruto Shunsuke
Research And Development Division Dainippon Pharmaceutical Co. Ltd.
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水田 泰之
Research Laboratories Damippon Pharmaceutical Co. Ltd.
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吉田 豊吉
Research Laboratories, Dainippon Pharmaceutical Co., Ltd.
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上田 昇三
Research Laboratories, Dainippon Pharmaceutical Co., Ltd.
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河島 勝良
Research Laboratories, Dainippon Pharmaceutical Co., Ltd.,
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上田 昇三
Research Laboratories Damippon Pharmaceutical Co. Ltd.
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門河 敏明
Research Laboratories, Damippon Pharmaceutical Co., Ltd.
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河島 勝良
Research Laboratories Dainippon Pharmaceutical Co. Ltd.
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門河 敏明
Research Laboratories Damippon Pharmaceutical Co. Ltd.
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吉田 豊吉
Exploratory Research Laboratories Dainippon Pharmaceutical Co. Ltd.
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