Syntheses of 2-Sulfamoylmethylbenzoxazole Derivatives and Determination of Their Anticonvulsant Activities
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概要
- 論文の詳細を見る
Some 2-sulfamoylmethylbenzoxazole derivatives were synthesized from 2-bromomethylbenzoxazole by reaction with sodium bisulfite, followd by chlorination and amination. Among them, 2-sulfamoylmethylbenzoxazole (5a) showed the strongest anticonvulsant activity, which was compared with that of 3-sulfamoylmethyl-1,2-benzisoxazole (I).
- 公益社団法人日本薬学会の論文
- 1981-08-25
著者
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宇野 準
大日本製薬株式会社総合研究所
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黒川 美貴雄
Research Laboratories, Dainippon Pharmaceutical Co., Ltd.
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増田 義信
Research Laboratories, Dainippon Pharmaceutical Co., Ltd.,
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宇野 準
大日本製薬株式会社
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宇野 準
大日本製薬
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宇野 準
Research Laboratory Dainippon Pharmaceutical Co. Ltd.
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黒川 美貴雄
大日本製薬株式会社創薬研究所
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宇野 準
Research Laboratories Dainippon Pharmaceutical Co. Ltd.
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