Studies on 3-Substituted 1,2-Benzisoxazole Derivatives. VII. Catalytic Reduction of 3-Sulfamoylmethyl-1,2-benzisoxazole and Reactions of the Resulting Products
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概要
- 論文の詳細を見る
Hydrogenation of 3-sulfamoylmethyl-1,2-benzisoxazole (1) gave ω-sulfamoyl-2-hydroxyacetophenone (3) and its imide (2). Treatment of 3 with acid afforded a new route to 1,2-benzoxathiin-4 (3H)-one-2,2-dioxide (5). The oxime of 3 (4) was recyclized to provide 1,2-benzisoxazole derivatives by treatment with acid or base. On pyrolysis 4 gave benzoxazole derivatives.
- 公益社団法人日本薬学会の論文
- 1982-01-25
著者
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宇野 準
大日本製薬株式会社総合研究所
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黒川 美貴雄
Research Laboratories, Dainippon Pharmaceutical Co., Ltd.
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宇野 準
大日本製薬株式会社
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宇野 準
大日本製薬
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宇野 準
Research Laboratory Dainippon Pharmaceutical Co. Ltd.
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黒川 美貴雄
大日本製薬株式会社創薬研究所
-
宇野 準
Research Laboratories Dainippon Pharmaceutical Co. Ltd.
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