Synthesis and Pharmacological Activities of 3-Phenyl-2-(1-piperazinyl)quinolines and Related Compounds(Medicinal Chemistry,Chemical)
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概要
- 論文の詳細を見る
Various 3-phenyl-2-piperazinylquinolines and their 3-methyl analogs were synthesized and the effects of these compounds on the central nervous system were evaluated pharmacologically in mice. Some compounds having a 3-phenyl group showed potent antagonism of maximal electroshock seizures, but the 3-methyl analogs had no significant activity in any of the tests.
- 公益社団法人日本薬学会の論文
- 1987-07-25
著者
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永井 保嵩
Research Laboratories Dainippon Pharmaceutical Co. Ltd.
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日野 克彦
Research Laboratories, Dainippon Pharmaceutical Co., Ltd.,
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宇野 準
Research Laboratories, Dainippon Pharmaceutical Co., Ltd.,
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日野 克彦
Research Laboratories Dainippon Pharmaceutical Co. Ltd.
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宇野 準
大日本製薬株式会社
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宇野 準
Research Laboratories Dainippon Pharmaceutical Co. Ltd.
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