Syntheses of 4-Aminodihydrothiazolopurines, 4-Aminodihydroimidazopurines and 4-Aminotetrahydropyrimidopurines
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概要
- 論文の詳細を見る
Cyclization reactions of 8-(β-haloethylthio) adenine, 8-(β-haloethylamino) adenines and 8-(γ-halopropylamino) adenine occurred at both of N^7 and N^9 of purine ring and pairs of cyclized compounds, 4-aminodihydrothiazolo [2,3-f]-and 4-aminodihydrothiazolo [3,2-e] purine, 4-aminodihydroimidazo [2,1-f]-and 4-aminodihydroimidazo [1,2-e] purines, and 4-aminotetrahydropyrimido [2,1-f]-and 4-aminotetrahydropyrimido [1,2-e] purine were obtained. Structures of 4-aminodihydrothiazolopurines were determined by desulfurization with Rany Ni and those of 4-aminodihydroimidazopurines and 4-aminotetrahydropyrimidopurines were determined by comparison of spectral data with those of N-cyclonucleosides.
- 公益社団法人日本薬学会の論文
- 1975-08-25
著者
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日野 克彦
Research Laboratories, Dainippon Pharmaceutical Co., Ltd.,
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入江 明
Research Laboratories, Dainippon Pharmaceutical Co., Ltd.,
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宇野 準
Research Laboratories, Dainippon Pharmaceutical Co., Ltd.,
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入江 明
Research Laboratories Dainippon Pharmaceutical Co. Ltd.
-
日野 克彦
Research Laboratories Dainippon Pharmaceutical Co. Ltd.
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宇野 準
大日本製薬株式会社
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宇野 準
Research Laboratories Dainippon Pharmaceutical Co. Ltd.
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