The Crystal and Molecular Structure of Racemic 11b-Methylbenzodiazepinooxazole

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概要

• 論文の詳細を見る

• The crystal structure of 11b-methylbenzodiazepinooxazole (MBDOZ) obtained from methanol solution was determined by X-ray diffraction techniques. MBDOZ crystallized in space group P_<bca> with cell dimensions a=25.293 (2) Å, b=8.483 (1) Å, and c=10.307 (1) Å. The centrosymmetric space group of P_<bca> with Z=8 demands that molecules in the crystal lattice form a racemic pair. Two diazepine moieties form a dimer with a hydrogen-bond net between the amide hydrogen and carbonyl oxygen (O_6) of each molecule. The conformations of the benzodiazepinooxazole ring system are discussed.

• 社団法人日本薬学会の論文
• 1990-01-25

著者

• 黒野 幸久

  神戸大学 大学院医学系研究科精神神経科学分野

• 池田 憲

  名古屋市立大学薬学部

• 池田 憲

  Faculty Of Pharmaceutical Sciences Nagoya City University

• 八代 有

  Faculty of Pharmaceutical Sciences Nagoya City University

• 八代 有

  名古屋市立大学薬学部

• 黒野 幸久

  Faculty of Pharmaceutical Sciences, Nagoya City University

• 桑山 知成

  Pharmacy, NTT Tokai General Hospital

• 畑野 研一郎

  Faculty of Pharmaceutical Sciences, Nagoya City University

• 畑野 研一郎

  Faculty Of Pharmaceutical Sciences Nagoya City University

• 桑山 知成

  Department of Pharmacy, NTT Tokai General Hospital

• 村上 明光

  Faculty of Pharmaceutical Sciences, Nagoya University

• 八代 有

  名古屋市立大学

• 桑山 知成

  Pharmacy Ntt Tokai General Hospital

• 村上 明光

  Faculty Of Pharmaceutical Sciences Nagoya University

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