Reactions of Phenyl Salicylates with Cyclodextrin in Alkaline Solution

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概要

• 論文の詳細を見る

• To isolate an intermediate, cyclodextrin salicylate, the reactions of phenyl salicylates with cyclodextrin were kinetically investigated in alkaline 22% acetonitrile solution. Even in the alkaline solution, the formation and accumulation of cyclodextrin salicylate was confirmed during the course of the reactions. The possible mechanism was discussed. The deacylation rate of cyclodextrin salicylate was considerably small compared with the uncatalyzed hydrolysis rates of phenyl salicylates and that of the acylation of cyclodextrin.

• 公益社団法人日本薬学会の論文
• 1979-04-25

著者

• 黒野 幸久

  神戸大学 大学院医学系研究科精神神経科学分野

• 池田 憲

  名古屋市立大学薬学部

• 池田 憲

  Faculty Of Pharmaceutical Sciences Nagoya City University

• 黒野 幸久

  Faculty of Pharmaceutical Sciences, Nagoya City University

• 四柳 智久

  Faculty of Pharmaceutical Sciences, Nagoya City University

• 四柳 智久

  Faculty Of Pharmaceutical Sciences Nagoya City University

• 深津 秀夫

  Faculty of Pharmaceutical Sciences, Nagoya City University

• 深津 秀夫

  Faculty Of Pharmaceutical Sciences Nagoya City University

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