Methanesulfonic Acid Derivative of N-Alkyl Aniline : Basicity of Aniline and Reactivity
スポンサーリンク
概要
- 論文の詳細を見る
Effect of N-alkyl substituents on the formation and hydrolysis rates of N-substituted aniline methanesulfonic acid derivatives were investigated in connection with substituted aniline derivatives. Their rates were satisfactorily correlated to the basicity of aniline derivatives which was corrected by hydration effect, that is Folkers, et al.'s H value.
- 公益社団法人日本薬学会の論文
- 1976-02-25
著者
-
黒野 幸久
神戸大学 大学院医学系研究科精神神経科学分野
-
池田 憲
Faculty Of Pharmaceutical Sciences Nagoya City University
-
黒野 幸久
Faculty of Pharmaceutical Sciences, Nagoya City University
-
四柳 智久
Faculty of Pharmaceutical Sciences, Nagoya City University
-
四柳 智久
Faculty Of Pharmaceutical Sciences Nagoya City University
-
山村 文子
Faculty of Pharmaceutical Sciences, Nagoya City University
-
山村 文子
Faculty Of Pharmaceutical Sciences Nagoya City University
関連論文
- 阪神淡路大震災と神戸市における自殺の動向 (特集 第42回精神保健シンポジウム(神戸)自殺予防を考える)
- RT-PCR法を用いた脳組織からの麻疹ウイルスの検出
- カンプトテシン誘導体含有 Collagen-poly (Hydroxyethyl Methacrylate) Hydrogel 製剤の固形癌療法への応用
- Kinetics and Mechanism of Tautomerism of a Hydroxy Schiff Base, N-[2-{2-Hydroxyethylimino(methyl)methyl}phenyl]-2-chlorpropamide, in Solution
- カンプトテシン誘導体とヒト血漿タンパクとの相互作用
- Regiospecific Nitration of Quinoline and isoquinoline through the Reissert Compounds
- Kinetics and Mechanism of the Acid-Base Equilibrium and the Hydrolysis of Benzodiazepinooxaziines
- 1,4-Benzodiazepine系医薬品の酸性水溶液中における挙動(第16報)Nuclear Magnetic Resonanceシフト試薬を利用したベンゾジアゼピノオキサゾール誘導体のcis/trans異性体の存在比率の算出
- Reissert-Type Reaction of N-Sulfonyl- or N-Acyl-phthalazinimum Salts with Trimethyl Phosphite and Crystal Structure of Dimethyl 2-Mesyl-1,2-dihydro-1-phthalazinylphosphonate
- The Crystal and Molecular Structure of Racemic 11b-Methylbenzodiazepinooxazole
- High-Performance Liquid Chromatographic Determination of the Stability of Sisomicin in Hydrophilic Petrolatum Ointment
- Reaction between Salicylic Acid and Zinc Oxide in the Presence of Water.
- Esterase-like Activity of Human Serum Albumin. VII. Reaction with p-Nitrophenyl 4-Guanidino-benzoate
- Thermal Analysis of Organic Medicinals. I. Detection of the Molecular Compound Formation by the Differential Thermal Analysis and by the Differential Scanning Calorimetry
- Effects of Drug Bindings on the Esterase-like Activity of Human Serum Albumin. VII. Subdivision of R-Type Drugs Inhibiting the Activity towards p-Nitrophenyl Acetate(Pharmaceutical)
- Esterase-like Activity of Human Serum Albumin. IV. Reactions with Substituted Aspirins and 5-Nitrosalicyl Esters
- Effects of Drug Binding on the Esterase-Like Activity of Human Serum Albumin. V. Reactive Site towards Substituted Aspirins
- Uptake of Phenothiazine Tranquilizers by Lauromacrogol Micelles in Acidic Solution
- Bile Salt-Induced Disintegration of Egg Phosphatidylcholine Liposomes : A Kinetic Study Based on Turbidity Changes
- A Two-Step Model of Disintegration Kinetics of Liposomes in Bile Salts
- Acid-Induced and Calcium-Induced Gelation of Alginic Acid : Bead Formation and pH-Dependent Swelling
- Effects of Monovalent Metal Ions and Propranolol on the Calcium Association in Calcium-Induced Alginate Gel Beads
- Complex Formation between Gallium(III) and Agriamycin in Aqueous Solutions
- Interaction of Calcium-Induced Alginate Gel Beads with Propranolol
- Micelle-Mediated Transport of Vitamin K_1 through Porous Membranes : Contribution of Phosphatidylcholine-Bile Salt Mixed Micelles
- Degradation of 4'-Methylumbelliferyl 4-Guanidinobenzoate Catalyzed by Human Serum Albumin
- pH-Dependent Degradation and Stabilization of Meclofenoxate Hydrochloride by Human Serum Albumin
- NaCl-INDUCED AGGREGATION OF EGG PHOSPHATIDYLCHOLINE LIPOSOMES
- The Rabbit as an Animal Model for Warfarin-Induced Hypoprothrombinemia : The Relationship between Prothrombin Time and Prothrombin Complex Activity
- The Interactions of Prostaglandins E_1,E_2 and F_ with Lauromacrogol
- Esterase-Like Activity of Human Serum Albumin. VIII. Reaction with Amino Acid p-Nitrophenyl Esters
- Multiple and Irreversible Binding of cis-Diamminedichloroplatinum(II) to Human Serum Albumin and Its Effect on Warfarin Binding
- 1,4-Benzodiazepine系医薬品の酸性水溶液中における挙動(第15報)11bメチル置換ベンゾジアゼピノオキサゾール系化合物のプロトン交換反応におけるイミニウム型構造の寄与
- Kinetics and Mechanism of the Acid-Base Equilibrium and the Subsequent Hydrolysis of 11b-Hydrogenbenzodiazepinooxazoles
- cis/trans Isomerization Rate of Oxazolam in Organic Solvents Measured by High-Performance Liquid Chromatography
- Solubilization of Steroid Hormones by Polyoxyethylene Lauryl Ether
- Solubilization of Benzoic Acid Derivatives by Polyoxyethylene Lauryl Ether
- Effect of Micellar Interactions on Base-Catalyzed Hydrolysis of Procaine
- Micellar Interaction of Tetracycline Antibiotics
- UTILIZATION OF HUMAN SERUM ALBUMIN AS DRUG ADDITIVES I. STABILIZER OF PROSTACYCLIN
- Effects of Drug Binding on the Esterase-Like Activity of Human Serum Albumin. III. : Evaluation of Reactivities of the Two Active Sites by Using Clofibric Acid as an Inhibitor
- Dissolution Kinetics of Barbital Polymorphs
- 1,4-Benzodiazepine系医薬品の酸性水溶液中における挙動(第12報) : 11bメチル置換ベンゾジアゼピノオキサゾール系化合物のプロトン交換反応
- Kinetics and Mechanism of Reversible Hydrolysis of 11b-Methylbenzodiazepinooxazoles
- Kinetics and Mechanism of the Acid-Base Equilibrium of Benzodiazeinooxazoles : Oxazolam Analogs
- フェノチアジン系薬物とアルキルスルホン酸とのイオン対形成およびアルコール溶媒和
- Hydrolysis Rate of Ethyl Cinnamates in the Presence of Cyclodextrin
- Inclusion Complexes of Cinnamic Acids with Cyclodextrins. Mode of Inclusion in Aqueous Solution
- Esterase-like Activity of Human Serum Albumin. V. Reaction with 2,4-Dinitrophenyl Diethyl Phosphate
- Ion Pair Formation of Tetracyclines-Haloacetates and Alcohol Solvation
- Inclusion Complexation of β-Cyclodextrin with Some Sulfonamides in Aqueous Solution
- Calcium-Induced Gelation of Alginic Acid and pH-Sensitive Reswelling of Dried Gels(Pharmaceutical)
- Effect of Cholesterol on Liposome Stability to Ultrasonic Disintegration and Sodium Cholate Solubilization(Pharmaceutical)
- Effects of Drug Binding on the Esterase Activity of Human Serum Albumin : Inhibition Modes and Binding Sites of Anionic Drugs
- Esterase-Like Activity of Human Serum Albumin : Structure-Activity Relationships for the Reactions with Phenyl Acetates and p-Nitrophenyl Esters
- Reactions of Phenyl Salicylates with Cyclodextrin in Alkaline Solution
- Effects of Drug Bindings on Esterase Activity of Human Serum Albumin. Dissociation Constants of the Complexes between the Protein and Drugs such as N-Arylanthranilic Acids, Coumarin Derivatives and Prostaglandins
- Methanesulfonic Acid Derivative of N-Alkyl Aniline : Basicity of Aniline and Reactivity
- Dissolution Phenomena of Organic Medicinals involving Simultaneous Phase Changes
- Studies on the Method of Thermal Analysis of Organic Medicinals. V.^ Semi-micro Apparatus for the Differential Thermal Analysis Permitting Direct Observation.
- Simultaneous Determination of Complexation Equilibrium Constants for Conjugated Guest Species by Extended Potentiometric Titration Method : On Barbiturate-β-Cyclodextrin System
- Inclusion Complexation of Barbiturates with β-Cyclodextrin in Aqueous Solution. I. Spectroscopic Study on the Mode of Interaction
- Esterase-like Activity of Human Serum Albumin. VI. : Reaction with p-Nitrophenyl Glycinate
- Photo-Stabilization and Solubilization of an Aldose Reductase Inhibitor, (E)-3-Carboxymethyl-5-[(2E)-methyl-3-phenylpropenylidene]rhodanine(ONO-2235), by Human Serum Albumin(Pharmaceutical)
- Studies on Decomposition and Stabilization of Drugs in Solution. I. Chemical Kinetic Studies on Aqueous Solution of Phenobarbital.
- Effects of Drug Binding on the Esterase-like Activity of Human Serum Albumin. VI. Reaction with Di-p-nitrophenyl Adipate
- The Behavior of 1,4-Benzodiazepine Drugs in Acidic Media, VI. : Hydrogen Exchange Reaction and Proton and Carbon-13 Nuclear Magnetic Resonance Spectra of Estazolam
- The Behavior of 1,4-Benzodiazepine Drugs in Acidic Media. V. : Kinetics of Hydrolysis of Flutazolam and Haloxazolam in Aqueous Solution
- The Behavior of 1,4-Benzodiazepine Drugs in Acidic Media. II. Kinetics and Mechanism of the Acid-Base Equilibrium Reaction of Oxazolam
- Methanesulfonic Acid Derivative of Drug. I. Reversible Hydrolysis Rate of Methanesulfonic Acid Derivative of Substituted Aniline and Biopharmaceutical Study on Sodium p-Phenetidinomethanesulfonate
- ヒト血清アルブミンの酵素的活性と薬物結合
- Electronic Properties of N-Heteroaromatics. XII. On the Mode of Interaction between Theophylline and Ethylenediamine in Aqueous Solution.
- Methanesulfonic Acid Derivative of Sulfonamide. II. Successively Reversible Hydrolysis of Sulfisoxazole Derivative
- Methanesulfonic Acid Derivative of Sulfonamides. I. Hydrolysis Rate in Vitro and Pharmacokinetics in Vivo
- Solubilization of Barbiturates by Polyoxyethylene Lauryl Ether
- Studies on Decomposition and Stabilization of Drugs in Solution. V. Stabilization of Barbiturate in Aqueous Solution of Polyalcohols and Sugars
- Studies on Decomposition and Stabilization of Drugs in Solution. IV. Effect of Dielectric Constant on the Stabilization of Barbiturate in Alcohol-Water Mixtures
- Kinetics and Mechanism of Transamination of Thiamine in the Presence of Bisulfite
- Effects of Drug Binding on the Esterase-Like Activity of Human Serum Albumin. IV. Application of an Analog Computer to Determination of the Multiple Dissociation Constants
- Release Rates of Substituted Aniline from Its Methanesulfonic Acid Derivative in Acid Region
- Effect of ortho-Substituents on Methanesulfonic Acid Derivative of Substituted Aniline
- Methanesulfonic Acid Derivative of p, p'-Diaminodiphenylsulfone. II. Pharmacokinetics and Availability of Parental Drug in Rabbit
- Methanesulfonic Acid Derivative of p, p'-Diaminodiphenylsulfone. I. Hydrolysis Rate in Vitro