Identification of a Methylated Tea Catechin as an Inhibitor of Degranulation in Human Basophilic KU812 Cells
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概要
- 論文の詳細を見る
We examined the constituents of tea that had an inhibitory effect on the degranulation process in the human basophilic cell line, KU812. Among the constituents purified from a extract of 'Benihomare'oolong tea by column chromatography, a methylated (-)-epigallocatechin gallate ((-)-epigallocatechin 3-O-(3-O-methyl) gallate) was found to inhibit the degranulation of KU812 cells that had been stimulated with calcium ionophore A23187. The inhibitory effect of this methylated (-)-epigallocatechin gallate on degranulation was greater than that of (-)-epigallocatechin gallate. This result indicates that methylation of (-)-epigallocatechin gallate may be an effective modification for the catechin to inhibit degranulation from human basophils.
- 社団法人日本農芸化学会の論文
- 2000-02-23
著者
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MAEDA-YAMAMOTO Mari
National Institute of Vegetable and Tea Science, NARO
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Tachibana Hirofumi
九州大学 農学部生物機能化学食糧化学
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MIYASE Toshio
School of Pharmaceutical Sciences, University of Shizuoka
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Miyase T
School Of Pharmaceutical Sciences University Of Shizuoka
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宮瀬 敏男
Department Of Pharmacognosy School Of Pharmaceutical Sciences
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Miyase Toshio
School Of Pharmaceutical Science University Of Shizuoka
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SANO Mitsuaki
School of Pharmaceutical Sciences, University of Shizuoka
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TACHIBANA Hirofumi
Division of Applied Biological Chemistry, Department ofBioscience and Biotechnology, Faculty of Agri
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YAMADA Koji
Division of Applied Biological Chemistry, Department ofBioscience and Biotechnology, Faculty of Agri
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Sunada Yousuke
Division Of Bioresources And Bioenvironmental Science Graduate School Kyushu University
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Tachibana Hirofumi
Division Of Bioresources And Bioenvironmental Science Kyushu University
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Tachibana Hirofumi
Faculty Of Agriculture Kyushu University
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Tachibana Hirofumi
Department Of Food Science And Technology Faculty Of Agriculture Kyushu University
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Maeda‐yamamoto Mari
National Agriculture And Bio‐oriented Res. Organization Sizuoka Jpn
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Sano M
National Institute Of Vegetable And Tea Science National Agriculture And Bio-oriented Research Organ
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Sano Mitsuaki
Dep. Of Food Sci. And Nutrition Nagoya Women's Univ.
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Sano Mitsuaki
School Of Pharmaceutical Sciences University Of Shizuoka
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Tachibana H
Faculty Of Agriculture Kyushu University
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Yamada Koji
Kyushu Univ. Fukuoka Jpn
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Maeda-yamamoto Mari
National Inst. Of Vegetable And Tea Sci. Naro
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Tian Huaize
Department Of Bioscience And Biotechnology Faculty Of Agriculture Kyushu University
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Yamada Koji
Division Of Bioresources And Bioenvironmental Science Graduate School Kyushu University
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SANO Mitsuaki
School of Pharmaceutical Science, University of Shizuoka
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