Studies on the Constituents of cimicifuga Species. XIX. Eight New Glycosides from Cimicifuga simplex WORMSK.
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概要
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Eight new glycosides were isolated from Cimicifuga simplex (Ranunculaceae), and their structures were determined to be 23-O-acetyl-7,8-didehydroshengmanol-3-O-α-L-arabinopyranoside (1), 24-epi-24-O-acetyl-7,8-didehydrohydroshengmanol-3-O-β-D-galactopyranoside (2), 7,8-didehydrocimigenol-3-O-β-D-galactopyranoside (3), 24-epi-24-O-acetylhydroshengmanol-3-O-β-D-galactopyranoside (4), cimigenol-3-O-β-D-galactopyranoside (5), 25-O-methylcimigenol-3-O-β-D-galactopyranoside (6), 25-O-acetylcimigenol-3-O-β-D-galactopyranoside (7) and 25-O-acetylcimigenol-3-O-β-D-glucopyranoside (8). Genuine aglycones were obtained by the hydrolysis of 1-7 with lactase F[Amano] and of 8 with cellulase T[Amano]4. Acerinol was prepared from 7,8-didehydrocimigenol and showed antilipemic effects.
- 公益社団法人日本薬学会の論文
- 1996-11-15
著者
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草野 昭子
Osaka University of Pharmaceutical Sciences
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Kusano Akiko
Osaka University Of Pharmaceutical Sciences
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MIYASE Toshio
School of Pharmaceutical Sciences, University of Shizuoka
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SHIBANO Makio
Osaka University of Pharmaceutical Sciences
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KUSANO Genjiro
Osaka University of Pharmaceutical Sciences
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Miyase T
School Of Pharmaceutical Sciences University Of Shizuoka
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Miyase Toshio
School Of Pharmaceutical Science University Of Shizuoka
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Kusano G
Osaka University Of Pharmaceutical Sciences
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Kusano Genjiro
Osaka University Of Phamaceutical Sciences
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KUSANO Genjirou
Osaka University of Pharmaceutical Sciences
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Kusano A
Osaka University Of Pharmaceutical Sciences
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