Studies on the Constituents of Broussonetia Species VIII. Four New Pyrrolidine Alkaloids, Broussonetines R, S, T, and V and a New Pyrroline Alkaloid, Broussonetine U, from Broussonetia kazunoki SIEB.^<1)>
スポンサーリンク
概要
- 論文の詳細を見る
Four new pyrrolidine alkaloids, broussonetines R, S, T, and V and a new pyrroline alkaloid, broussonetine U were isolated from the branches of Broussonetia kazinoki SIEB.(Moraceae)in low yield. Broussonetines R, S and T were formulated as(2R, 3R, 4R, 5R)-2-hydroxymethyl-3, 4-dihydroxy-5-{(1R)-1-hydroxy-3-[6-(4-hydroxybutyl)-cyclohexy-2-on-1(6)-enyl]propyl}pyrrolidine(1), (2R, 3R, 4R, 5R)-2-hydroxymethyl-3, 4-dihydroxy-5-[(1R, 10S)-1, 10, 13-trihydroxytridecyl]pyrrolidine(2), (2R, 3R, 4R, 5R)-2-hydroxymethyl-3, 4-dihydroxy-5-[(1R, 5S)-1, 5, 13-trihydroxy-10-oxo-tridecyl]pyrrolidine(3).And broussonetines U and V were propsed to be(2S, 3S, 4S)-2-hydroxymethyl-3, 4-dihydroxy-5-(9-oxo-13-hydroxytridecyl)-5-pyrroline (4), 2R, 3S, 4R, 5R)-2-hydroxymethyl-3, 4-dihydroxy-5-[(E)-9-oxo-13-hydroxy-3-tridecenyl]pyrrolidine(5), respectively, by spectroscopic and chemical methods.
- 公益社団法人日本薬学会の論文
- 2001-04-01
著者
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SHIBANO Makio
Osaka University of Pharmaceutical Sciences
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KUSANO Genjiro
Osaka University of Pharmaceutical Sciences
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Shibata M
Fumakilla Ltd.
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TSUKAMOTO Daisuke
Osaka University of Pharmaceutical Sciences
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OKAMOTO Rieko
Osaka University of Pharmaceutical Sciences
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Kusano G
Osaka University Of Pharmaceutical Sciences
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Kusano Genjiro
Osaka University Of Phamaceutical Sciences
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