Studies on the Constituents of Broussonetia Species. I. Two New Pyrrolidine Alkaloids, Broussonetines C and D, as β-Galactosidase and β-Mannosidase Inhibitors from Broussonetia kazinoki SIEB.
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概要
- 論文の詳細を見る
Two new pyrrolidine alkaloids called broussonetines C and D were isolated from the branch of Broussonetia kazinoki SIEB. (Moraceae). Broussonetines C and D were formulated as (2R, 3R, 4R, 5R)-2-hydroxymethyl-3,4-dihydroxy-5-(10-oxo-hydroxytridecyl)pyrrolidine (1) and (2R, 3R, 4R, 5R)-2-hydroxymethyl-3,4-dihydroxy-5-(9-oxo-13-hydroxytridecyl)pyrrolidine (2), respectively, by spectroscopic and chemical methods. 1 and 2 showed an inhibition to β-galactosidase and β-mannosidase.
- 公益社団法人日本薬学会の論文
- 1997-03-15
著者
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SHIBANO Makio
Osaka University of Pharmaceutical Sciences
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KUSANO Genjiro
Osaka University of Pharmaceutical Sciences
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Kitagawa S
Niigata Univ. Pharmacy And Applied Life Sci. Niigata Jpn
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Kitagawa Shuji
Kobe Pharmaceutical University
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Kitagawa S
Niigata College Of Pharmacy
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Shibano M
Osaka University Of Pharmaceutical Sciences
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Kusano G
Osaka University Of Pharmaceutical Sciences
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Kusano Genjiro
Osaka University Of Phamaceutical Sciences
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KITAGAWA Satoshi
Osaka University of Pharmaceutical Sciences
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