Phylogenetic Relationship of Six Glycyrrhiza Species Based on rbcL Sequences and Chemical Constituents

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概要

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• The nucleotide sequences of ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit gene (rbcL) of Glycyrrhiza glabra, G. uralensis, G. inflata, G. echinata, G. macedonica and G. pallidiflora have been determined to construct their phylogenetic tree. Based on these sequences, the six Glycyrrhiza species were divided into two groups : three, G. glabra, G. uralensis, and G. inflata, which produce glycyrrhizin as a major saponin, and the others, G. echinata, G. macedonica and G. pallidiflora, which produce macedonoside C as a major saponin. Among the three glycyrrhizin-producing species, only two nucleotide substitutions were observed between the rbcL sequences of G. glabra and G. uralensis, and the sequence of G. uralensis was identical to that of G. inflata, indicating that G. uralensis and G. inflata are closely related. Among the three macedonoside C-producing species, only one nucleotide substitution was observed between those of G. echinata and G. macedonica, indicating that these two species are also closely related.

• 公益社団法人日本薬学会の論文
• 2000-05-01

著者

• INOUE Kenichiro

  Gifu Pharmaceutical University

• Hayashi H

  Univ. Tokyo Tokyo Jpn

• SHIBANO Makio

  Osaka University of Pharmaceutical Sciences

• KUSANO Genjiro

  Osaka University of Pharmaceutical Sciences

• Hayashi H

  Drug Research Division Dainippon Sumitomo Pharma Co. Ltd.

• Hayashi Hideya

  Pharmaceuticals And Biotechnology Laboratory Japan Energy Corporation

• Hayashi H

  Pharmaceuticals & Biotechnology Laboratory Japan Energy Corporation

• HAYASHI Hiroaki

  Gifu Pharmaceutical University

• Inoue K

  Kobe Pharmaceutical Univ. Kobe Jpn

• HIRAOKA Noboru

  Niigata College of Pharmacy

• IKESHIRO Yasumasa

  Niigata College of Pharmacy

• Kusano Genjiro

  Osaka University Of Phamaceutical Sciences

• Hiraoka N

  Faculty Of Pharmacy Niigata University Of Pharmacy And Applied Life Sciences

• Hiraoka Noboru

  Niigata University Of Pharmacy And Applied Life Sciences

• HOSONO Noriko

  Niigata College of Pharmacy

• KONDO Mieko

  Niigata College of Pharmacy

• YAMAMOTO Hirobumi

  School of Pharmaceutical Sciences, Nagasaki University

• TANAKA Toshihito

  Gifu Pharmaceutical University

• 渋谷 雅明

  Riken Plant Science Center

• Inoue Kenichiro

  Gifu Pharmaceutical Univ. Gifu Jpn

• Ikeshiro Yasumasa

  Niigata University Of Pharmacy And Applied Life Sciences

• Yamamoto Hirobumi

  Laboratory Of Medicinal Plant Garden Nagasaki University School Of Pharmaceutical Sciences

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