Studies on the Constituents of Cimicifuga Species. XX. Absolute Stereostructures of Cimicifugoside and Actein from Cimicifu simplex WORMSK.

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概要

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• The absolute stereostructues of cimicifugoside (1) and actein (2) from Cimicifuga simplex were established by X-ray crystal analysis of 26(S)-O-methylcimicifugenin A (1cS) prepared from 1,negative CD curves of 26-O-methyl-3-keto-cimicifugenins (1dS, 1dR), comparative analysis of ^1H- and ^<13>C-NMR spectra of 1,2 and their derivatives, and preparation of 2 from 1 by hydrogenation : 20(R), 23(R), 24(R), 25(S), 26(R, S)-16β : 23; 23 : 26; 24 : 25-triepoxy-12β-acetoxy-3β, 26-dihydroxy-9,19-cyclolanost-7-ene 3-O-β-D-xylopyranoside for 1 and 20(R), 23(R), 24(R), 25(S), 26(R, S)-16β : 23; 23 : 26; 24 : 25-triepoxy-12β-acetoxy-3β, 26-dihydroxy-9,19-cyclolanostane 3-O-β-D-xylopyranoside for 2.

• 1998-03-15

著者

• 草野 昭子

  Osaka University of Pharmaceutical Sciences

• IN Yasuko

  Osaka University of Pharmaceutical Sciences

• ISHIDA Toshimasa

  Osaka University of Pharmaceutical Sciences

• Kusano Akiko

  Osaka University Of Pharmaceutical Sciences

• MIYASE Toshio

  School of Pharmaceutical Sciences, University of Shizuoka

• TAKAHIRA Masayuki

  Osaka University of Pharmaceutical Sciences

• SHIBANO Makio

  Osaka University of Pharmaceutical Sciences

• KUSANO Genjiro

  Osaka University of Pharmaceutical Sciences

• In Yasuko

  Osaka University Of Pharmaceutical Science

• Miyase T

  School Of Pharmaceutical Sciences University Of Shizuoka

• Miyase Toshio

  School Of Pharmaceutical Science University Of Shizuoka

• Kusano G

  Osaka University Of Pharmaceutical Sciences

• Kusano Genjiro

  Osaka University Of Phamaceutical Sciences

• Ishida Toshimasa

  Osaka Univ. Of Pharmaceutical Sciences

• Kusano A

  Osaka University Of Pharmaceutical Sciences

• Ishida Toshimasa

  Osaka College of Pharmacy

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