Enantioselective Synthesis of a Phenylalanine Library Containing Alkyl Groups on the Aromatic Moiety : Confirmation of Stereostructure by X-Ray Analysis

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概要

• 論文の詳細を見る

• Six phenylalanine analogues containing 2'-methyl-, 2',6'-dimethyl-, 2'-ethyl-6'-methyl-, 2'-isopropyl-6'-methyl-, 2',4',6'-trimethyl-, and 3',5'-dimethyl-L-phenylalanine were synthesized enantioselectively through asymmetric hydrogenation of acetamidoacrylate derivatives. Enzymatic digestion and X-ray analysis supported the L-configuration of the phenylalanine derivatives obtained.

• 公益社団法人日本薬学会の論文
• 2006-06-01

著者

• 石田 尚行

  電気通信大量子物質工

• 津田 喜典

  金沢大学薬学部

• 石田 尚之

  電通大電気通信学部

• 石田 尚之

  電通大量子物質工

• IN Yasuko

  Osaka University of Pharmaceutical Sciences

• ISHIDA Toshimasa

  Osaka University of Pharmaceutical Sciences

• Yokoi T

  Faculty Of Pharmaceutical Sciences Kobe Gakuin University

• Tsuda Yuko

  Faculty Of Pharmaceutical Sciences Kobe Gakuin University:cooperative Research Center Of Life Scienc

• Lazarus L

  Medicinal Chemistry Group Lpc National Institute Of Environmental Health Sciences

• Tsuda Y

  Faculty Of Pharmaceutical Sciences Kobe Gakuin University

• In Y

  Osaka Univ. Pharmaceutical Sci. Osaka Jpn

• In Yasuko

  Osaka University Of Pharmaceutical Science

• Tsuda Yuko

  Faculty Of Pharmaceutical Science Kobe Gakuin University

• 津田 喜典

  金沢大

• MINOURA Katsuhiko

  Osaka University of Pharmaceutical Sciences

• Ishida T

  Osaka Univ. Pharmaceutical Sci. Osaka

• LI Tingyou

  The Graduate School of Food and Medicinal Sciences and Faculty of Pharmaceutical Sciences, Kobe Gaku

• TSUDA Yuko

  The Graduate School of Food and Medicinal Sciences and Faculty of Pharmaceutical Sciences, Kobe Gaku

• LAZARUS Lawrence

  Medicinal Chemistry Group, Laboratory of Pharmacology and Chemistry, National Institute of Environme

• OKADA Yoshio

  The Graduate School of Food and Medicinal Sciences and Faculty of Pharmaceutical Sciences, Kobe Gaku

• Okada Y

  Faculty Of Pharmaceutical Sciences Kobe Gakuin University

• Li Tingyou

  The Graduate School Of Food And Medicinal Sciences And Faculty Of Pharmaceutical Sciences Kobe Gakui

• Ishida T

  Departments Of Biochemistry Shiga University Of Medical Science

• Okada Yoshihito

  Department Of Pharmacognosy And Phytochemistry Meiji College Of Pharmacy

• Lazarus Lawrence

  Medicinal Chemistry Group Lpc National Institute Of Environmental Health Sciences

• Ogino Yoshio

  The Third Department Of Internal Medicine Yeikyo University School Of Medicine

• Tsuda Y

  Faculty Of Pharmaceutical Sciences And High Technology Research Center Kobe Gakuin University

• Ishida Toshimasa

  Osaka Univ. Of Pharmaceutical Sciences

• Minoura K

  Department Of Physical Chemistry Osaka University Of Pharmaceutical Sciences

• Ogino Y

  Teikyo Univ. School Of Medicine Chiba

• Inamori Yoshihiko

  Osaka College Of Pharmacy

• Ishida Toshimasa

  Dep. Of Physical Chemistry Osaka Univ. Of Pharmaceutical Sciences

• Ishida Toshimasa

  Osaka College of Pharmacy

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