Possible Role of Each Repeat Structure of the Microtubule-Binding Domain of the Tau Protein in In Vitro Aggregation

スポンサーリンク

概要

• 論文の詳細を見る
• 2005-10-01

著者

• 石田 尚行

  電気通信大量子物質工

• YAO Tian-Ming

  Department of Chemistry, Tongji University

• ISHIDA Toshimasa

  Osaka University of Pharmaceutical Sciences

• MINOURA Katsuhiko

  Osaka University of Pharmaceutical Sciences

• Sasaki Masahiro

  Behavioral And Medical Sciences Research Consortium

• TOMOO Koji

  Osaka University of Pharmaceutical Sciences

• Koji Tomoo

  Department Of Physical Chemistry Osaka University Of Pharmaceutical Sciences

• Iwashita T

  Suntory Institute For Bioorganic Research

• Yao T‐m

  Osaka University Of Pharmaceutical Sciences

• Yao Tian-ming

  Department Of Chemistry Tongji University

• HIRAOKA Shuko

  Osaka University of Pharmaceutical Sciences

• SUMITA Miho

  Behavioral and Medical Sciences Research Consortium

• TANIGUCHI Taizo

  Behavioral and Medical Sciences Research Consortium

• Sumida Miho

  Behavioral And Medical Sci. Res. Consortium Hyogo Jpn

• Taniguchi Taizo

  Biosignal Research Center Kobe University

• Ishida Toshimasa

  Osaka Univ. Of Pharmaceutical Sciences

• Taniguchi Taizo

  Behavioral And Medical Sci. Res. Consortium Hyogo Jpn

• Minoura K

  Department Of Physical Chemistry Osaka University Of Pharmaceutical Sciences

• Ishida Toshimasa

  Dep. Of Physical Chemistry Osaka Univ. Of Pharmaceutical Sciences

• Ishida Toshimasa

  Osaka College of Pharmacy

関連論文

• Flavonoids inhibit heparin-induced aggregation of the third repeat (R3) of microtubule-binding domain of Alzheimer's tau protein
• 27aQJ-11 RE-3dヘテロ金属分子磁性体の交換相互作用と磁性(量子スピン系(二次元系及びその他),領域3,磁性,磁気共鳴)
• 20aQH-7 RE-3dヘテロ金属分子磁性体の交換相互作用と磁性(20aQH 量子スピン系(クラスター系及び一般),領域3(磁性,磁気共鳴))
• Studies on the Constituents of Cimicifuga Species. XX. Absolute Stereostructures of Cimicifugoside and Actein from Cimicifu simplex WORMSK.
• Illumination-induced Magnetization Enhancement of the Weak Ferromagnet [Fe(N_3)_2(pm)] (pm = Pyrimidine)
• 24pPSB-2 S=1/2反強磁性鎖の磁化過程における交替磁場の影響(量子スピン系,化合物磁性,スピングラス・ランダム系,アモルファス系,フラストレーション系,磁気共鳴一般,磁性一般,領域3(磁性,磁気共鳴))
• 27aPS-106 S=1/2一次元反強磁性鎖Cu-pyrimidineの強磁場磁化過程(領域3ポスターセッション : 希土類合金,化合物磁性,薄膜・人工格子,スピングラス,フラストレーション,量子スピン系,実験技術開発等)(領域3)
• 21aTC-8 交替磁場が存在する 1 次元反強磁性鎖 Cu-pyrimidine の強磁場磁化
• 超分子的に制御できる分子磁性
• Low - Temperature Magnets M[N(CN)_2]_2(pyrimidine)(M=Fe and Co) with a 3 - D Network
• One-Dimensional S=1 Ferromagnetic Chain Formed by a Square Ni_2S_2Motif in Ni(qt)_2(qt=Quinoline-8-thiolate)
• The Experimental Deformation Electron-Density Distributions of 4-Arylmethyleneamino-2,2,6,6-tetramethyl-1-piperidyloxyl (TEMPO) Radicals: Relations between Electron Densities and Intermolecular Interactions
• 27aYQ-12 有機磁性体4-Py-CH=N-TEMPOのμSR研究
• 30p-J-6 μSR実験法を用いた有機ラジカル強磁性体Ar-CH=N-TEMPOの磁性研究II
• 30p-J-4 有機強磁性体p-Cl-C_6H_4CH=N-TEMPOにおける圧力誘起強磁性-反強磁性転移
• Ferromagnetic and Antiferromagnetic Phases of 4-(4-Iodobenzylideneamino)-2,2,6,6-tetramethylpiperidin-1-yloxyl
• 28a-YH-5 μSR実験法を用いた有機ラジカル強磁性体Ar-CH=N-TEMPOの磁性研究
• Pyrimidine-Bridged Cobalt(II) Complexes with a Chiral 3-D Network Showing Weak Ferromagnetism
• 1p-Y-13 μSR実験法を用いた有機ラジカル強磁性体Ph-CH=N-TEMPOの磁性研究
• 1p-Y-12 有機強磁性体TEMPOの加圧効果
• 6a-YH-2 μSR実験法を用いた有機ラジカル強磁性体Ar-CH=N-TEMPOの磁性研究
• Ferromagnetic Dimer of π-Conjugated Organic Free Radicals 9, 9-Bis(p-tolyl)-9, 10-dihydroacridin-10-yloxyl
• Flavonoids Inhibit Heparin-Induced Aggregation of the Third Repeat (R3) of Microtubule-Binding Domain of Alzheimer's Tau Protein
• Comparison of Conformations of Tetrapeptide Diastereomers Containing α-Phenyl-α-(2-pyridyl)glycine
• 超分子的に制御できる分子磁性
• Structual Analyses for Asymmetric Derivatives of Ascidiacyclamide by X-ray Diffraction and NMR Spectroscopy
• X-Ray Molecular and Crystal Structure of Imidazolopyrroloquinoline, a Main Reaction Product of Pyrroloquinolinequinone (PQQ) and L-Tryptophan in Vitro
• Unusual Intermolecular Short Contacts of C…C = 2.3Å in Crystal Structure of Copper Complex of Schiff Base of Vitamin B_6 Phosphate Ester; Does It Reveal an Intermediate Structure to σ-Covalent Bond Formation ?
• Crystal Structure of Hybrid Dipeptide, (2-Carboxyethyl)-cytosine-1-yl-L-threonine Monohydrate
• Crystal Structure of Hybrid Dipeptide, Cytosinyl-L-tyrosine
• Conformation and Sodium Coordinate Forms of an Endothelin Inhibitor BQ123・Na, Cyclo(-D-Trp-D-Asp^~-Pro-D-Val-Leu-)・Na^+, in the Crystal
• Polymorphism and C-H…O Interaction of Wortmannin, a Phosphatidylinositol 3-Kinase Inhibitor
• Crystal Structure of 3, 4-Dihydroxy-6-fluoro-DL-phenylalanine Monohydrate Used as a Positron Emission Tomography Imaging Ligand
• Interaction Modes between N7-Quarternized Guanine and Cytosine-Containing Dipeptides
• Crystal Structure of Hybrid Dipeptide, Uracil-1-yl-(2-carboxyethyl)-glycine
• Crystal Structure of Cytosine and Alanine Hybrid Dipeptide, Cytosine-1-yl-(2-carboxyethyl)-L-alanine
• Metal-Azide-Pyrimidine Complexes M(N_3)_2(pm) with a Three-Dimensional Network Showing Weak Ferromagnetism for M = Mn and Fe and Antiferromagnetism for M = Co and Ni
• Low-Temperature Heat Capacities and Ferromagnetic Phase Transition of the Organic Free Radical Ferromagnet, 4-(4-Chlorobenzylideneamino)-2,2,6,6-tetramethylpiperidin-1-oxyl (CATMP)
• Aggregation Feature of Fluorine-Substituted Benzene Rings and Intermodular C-H…F Interaction: Crystal Structure Analyses of Mono- and Trifluoro-L-phenylalanines
• Turnip Mosaic Virus Genome-Linked Protein VPg Binds C-Terminal Region of Cap-Bound Initiation Factor 4E Orthologue Without Exhibiting Host Cellular Specificity
• Opioid Peptide-Like Activities of Fulicin, Fulicin Gene-Related Peptides, and Their Synthetic Analogs
• μSR of the Organic Radical Ferromagnet, 4-(p-Chlorobenzylideneamino)-2, 2, 6, 6-tetramethylpiperidin-1-yloxyl
• Organic Radicals Exhibiting Intermolecular Ferromagnetic Interactions with High Probability: 4-Arylmethyleneamino-2,2,6,6-tetramethylpiperidin-1-yloxyls and Related Compounds
• Study on the Structure Activity Relationship of a Phytosiderophore, Mugineic Acid
• Study on the Relationship between Structure and Metal Complexation Ability of Mugineic Acid
• Domain-dependent Interaction of Eukaryotic Initiation Factor eIF4A for Binding to Middle and C-terminal Domains of eIF4G
• Role of Each Repeat Peptide in Aggregation of Tau Microtubule-binding Domain
• Effect of DNA on Filament Formation of Tau Microtubule-Binding Domain : Structural Dependence of DNA
• Marked Difference Between Self-aggregations of First and Fourth Repeat Peptides on Tau Microtubule-binding Domain in Acidic Solution
• Study of Self-Aggregation Mechanism of Microtubule-Binding Domain of Tau Protein
• Effect of N-Terminal Region of eIF4E and Ser65-Phosphorylation of 4E-BP1 on Interaction between eIF4E and 4E-BP1 Fragment Peptide
• N-terminal Secondary Structures of Second and Third Repeat Fragments Responsible for Self-assembly of Tau Microtubule-binding Domain
• PH-Dependent Filament Formation of Repeat Peptide of Microtubule-binding Domain of Tau Protein
• Possible Role of Each Repeat Structure of the Microtubule-Binding Domain of the Tau Protein in In Vitro Aggregation
• Solvent-dependent Conformational Change of Third Repeat Fragment of Microtubule-binding Domain Responsible for Filament Formation of Tau Protein
• Crystal and Molecular Structure of an (S)-(+)-Enantiomer of Modafinil, a Novel Wake-Promoting Agent
• Conformational Analysis of Four Repeat Fragments in Tau Microtuble Binding Domain
• Analysis of aggregation mechanism of microtuble binding domain in tau protein
• Proposed Mechanism of Ferromagnetic Interaction of Organic Ferromagnets : 4-(Arylmethyleneamino)-2,2,6,6-tetramethylpiperidin-1-oxyls and Related Compounds
• Ferromagnetism in Organic Radical Crystal of 4-(p-Chlorobenzylideneamino)-2,2,6,6-tetramethylpiperidin-1-oxyl
• Syntheses and Structures of Novel Fused-Ring Systems Containing Six or Seven Sulfur Atoms : 2,3:5,6-Bis(ethylenedithio)thieno[3,2-b]thiophene and 3,4:6,7-Bis(ethylenedithio)thieno[3,2-c][1,2]dithiin
• An Organic Ferromagnet with a Tc of 0.4 K. 4-(p-Phenylbenzylideneamino)-2,2,6,6-tetramethylpiperidin-1-oxyl
• A New Organic Ferromagnet: 4-Benzylideneamino-2,2,6,6-tetramethylpiperidin-1-oxyl
• Enantioselective Synthesis of a Phenylalanine Library Containing Alkyl Groups on the Aromatic Moiety : Confirmation of Stereostructure by X-Ray Analysis
• Binding Diversity of a Noncovalent-Type Low-Molecular-Weight Serine Protease Inhibitor and Function of a Catalytic Water Molecule : X-Ray Crystal Structure of PKSI-527-Inhibited Trypsin
• Intermolecular Association Model of Antifungal Polyene Macrolide via Concerted =C-H…O Interactions : X-ray Crystal Structure Analysis and Ab Initio Molecular-Orbital Calculations of Chainin
• Difference between Enzymatic and Chemical N-methylations of Protoberberine-Type Alkaloid, Dependent on the Stereoisomer of (-)-N-methyl-7, 8, 13, 13a-tetrahydroberberinium Salt
• Functional Analysis of C-Terminal Amide in Bioactivity of Endomorphin-2 : Conformational Comparison with Its Unamidated Peptide in DMSO Solution
• Structural/Physicochemical Properties of Corycavidine, a Key Intermetabolite in the Biosynthesis of Isoquinoline Alkaloids, Elucidated by X-Ray Crystallography, Solution Conformation and Thermal Behavior Analyses, and Energy Calculations
• Copper(II) Ion-Catalyzed and Molecular Packing-Dependent Dimerization of Pyridoxal 5-Phosphate-Pyridoxamine 5-Phosphate Schiff Base as a Structural Model for in Vitro Transformation of Amino Acid by Pyridoxal 5-Phosphate : X-Ray Crystal Structural investi
• Molecular Ferromagnet, PM[VO(hfac)_2]_2 (PM=pyrimidine, hfac = 1,1,1,5,5,5-hexafluoropenta-2,4-dionate). Ferromagnetic Assembly of Ground High-Spin Molecules
• Structural Requirement for Chiral Recognition of Amino Acid by (18-Crown-6)-tetracarboxylic Acid : Binding Analysis in Solution and Solid States
• Conformational Comparison of μ-Selective Endomorphin-2 with its C-Terminal Free Acid, Studied by ^1H-NMR Spectroscopy and X-Ray Structure Analysis
• Molecular Cynamics Simulations of Bovine Cathepsin B and Its Complex with CA074
• Comparison of Efficiencies of the Fused Heterocyclic Compounds, 9H-Xanthene-2, 7-diols, and Related Chain-Breaking Phenolic Antioxidants
• Characterization of an End Product in a Copper(II)-Mediated Nonenzymatic Reaction of Vitamin B_6 with Amino Acid: X-Ray Crystal Structure of a Dimer of Cu(II). [Pyridoxal 5-Phosphate-Pyridoxamine 5-Phosphate Schiff Base]. 7H_2O
• Binding Mode of CA074, a Specific Irreversible Inhibitor, to Bovine Cathepsin B as Determined by X-Ray Crystal Analysis of the Complex
• The Curie Temperature of Anisotropic Heisenberg Ferromagnet with Mixed Spins of S=1/2 and S=1
• Structural Studies of C-Amidated Amino Acids and Peptides : Crystal Structures of Z-Gly-Phe-NH_2,Tyr-Lys-NH_2,and Asp-Phe-NH_2
• Solvent-Dependent Conformation of the Third Repeats Fragment in the Microtubule-Binding Domain of Tau Protein, Analyzed by ^1H-NMR Spectroscopy and Molecular Modeling Calculation
• Aggregation Analysis of the Microtubule Binding Domain in Tau Protein by Spectroscopic Methods
• Inhibitory Behavior of Cyanidine and Methylene Blue for Filament Formation of Tau Microtubule-binding Domain
• Structural Studies of [2',6'-Dimethyl-L-tyrosine^1]Endomorphin-2 Analogues Containing Proline Mimics
• Importance of Tyrosine Residue for Filament Formation of Tau Microtubule-binding Domain
• Structural Scaffold of 18-Crown-6 Tetracarboxylic Acid for Optical Resolution of Chiral Amino Acid : X-Ray Crystal Analyses of Complexes of D- and L-Isomers of Serine and Glutamic Acid
• Conformational Study of Repeat Fragments in Microtuble Binding Domain of Tau Protein
• Aggregation Analysis of Microtubule Binding Domain in Tau Protein by Spectroscopic Method
• Total Synthesis of cis,cis-Ceratospongamide and It's Thermal Isomerization : What is the Real Structure of the Isomerization Product?
• Inclusion Effect and Structural Basis of Cyclodextrins for Increased Extraction of Medicinal Alkaloids from Natural Medicines
• Molecular Conformation of Aureobasidin A, a Potent Antifungal Cyclic Depsipeptide : X-Ray Structure Analysis
• Intermolecular Ferromagnetic Interaction of 4-Benzylideneamino-2,2,6,6-tetramethylpiperidin-1-oxy1
• Intermolecular Ferromagnetic Interaction of 4-(2-Naphthylmethyleneamino)-2,2,6,6-tetramethylpiperidin-1-oxyl
• Importance of Tyr310 residue in the third repeat of microtubule binding domain for filament formation of tau protein
• 希釈冷凍機を用いた極低温のミューエスアール
• Pyrimidines as Ferromagnetic Exchange Couplers in Dinuclear Oxovanadium(IV) Coplexes
• Importance of CH-π Interaction Between I308 and Y310 Residues in the Third Repeat of Microtubule Binding Domain for Tau Filament Formation
• Comparison of the Efficiencies of the Fused Heterocyclic Compounds, 9H-Xanthene-2,7-diols, and Related Chain-Breaking Phenolic Antioxidants
• Synthesis and Conformational Analysis of Dcp-Containing Homo-Oligopeptides
• CH-π Interaction between I308 and Y310 Residues is Required for Self Assembly of Full Length Tau
• The Impacts of Hg(II) Tightly Binding on the Alzheimer's Tau Construct R3 : Misfolding and Aggregation

もっと見る 閉じる

スポンサーリンク