Three Trihydroxypiperidines, Glycosidase Inhibitors, from Eupatorium fortunei TURZ
スポンサーリンク
概要
- 論文の詳細を見る
A new stereoisomer, mesotrihydroxypiperidine (I) was isolated along with its two known stereoisomers, 3α,4β,5α-trihydroxypiperidine (II) and 3β,4β,5α-trihydroxypiperidine (III) from Eupatorium fortunei TURZ. The inhibitory activities (IC_<50>) on α-glucosidase were 3.70μM for I, 1.54μM for II and 1.88μM for III. The inhibitory activity of II on β-glucosidase was 0.51μM, that of I on α-mannosidase was 1.88μM and that of III on β-galactosidase was 3.76 μM.
- 日本生薬学会の論文
- 1995-09-20
著者
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SHIBANO Makio
Osaka University of Pharmaceutical Sciences
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KUSANO Genjiro
Osaka University of Pharmaceutical Sciences
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Kusano Genjiro
Osaka University Of Phamaceutical Sciences
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Sekioka Toshikai
Osaka University Of Pharmaceutical Sciences
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