Antimicrobial Activity of the Thiosulfinates Isolated from Oil-Macerated Garlic Extract
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概要
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Three thiosulfinates were isolated from oil-macerated garlic extract, and their structures were identified as 2-propene-1-sulfinothioic acid S-(Z, E)-1-propenyl ester [AllS (O) SPn-(Z, E)], 2-propenesulfinothioic acid S-methyl ester [AllS (O) SMe], and methanesulfinothioic acid S-(Z, E)-1-propenyl ester [MeS (O) SPn-(Z, E)]. This is the first report of isolating these thiosulfinates from oil-macerated garlic extract. Antimicrobial activities of AllS (O) SPn-(Z, E) and AllS (O) SMe against Gram-positive and negative bacteria and yeasts were compared with 2-propene-1-sulfinothioic acid S-2-propenyl ester [AllS (O) SAll, allicin] which is well-known as the major thiosulfinate in garlic. Antimicrobial activity of AllS (O) SMe and AllS (O) SPn-(Z, E) were comparable and inferior to that of allicin, respectively. This result suggested that the antimicrobial activity of 2-propene sulfinothioic acid S-alk (en) yl esters were affected by alk (en) yl groups. The order for antimicrobial activity was : allyl ≥ methyl > propenyl.
- 社団法人日本農芸化学会の論文
- 1999-03-23
著者
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YOSHIDA Hiroko
Division of Food and Nutrition, Nakamura Gakuen Junior College
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FUKUDA Hiroyuki
Biodevelopment Division, Central Institute, Nagoya Seiraku Co., Ltd.
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FUJINO Tsuchiyoshi
Biodevelopment Division, Central Institute, Nagoya Seiraku Co., Ltd.
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Suzuki Atsushi
Biodevelopment Division Central Institute Nagoya Seiraku Co. Ltd.
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Suzuki Atsushi
Department Of Applied Biological Chemistry Faculty Of Agriculture University Of Niigata
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Suzuki Atsushi
Synthetic Crystal Research Laboratory Faculty Of Engineering Nagoya University
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Suzuki Atsushi
Department Of Pathology Obstetrics And Gynecology Keio University School Of Medicine
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Suzuki Atsushi
Basic Research Department Prima Meat Packers Co. Ltd.
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Suzuki Atsushi
Department Of Applied Biochemistry Faculty Of Agriculture University Of Niigata
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Suzuki A
Department Of Obstetrics And Gynecology Keio University School Of Medicine
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Suzuki A
Department Of Applied Biological Chemistry Faculty Of Agriculture University Of Niigata
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YOSHIDA Hisae
Biodevelopment Division, Central Institute, nagoya Seiraku Co., Ltd.
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KATSUZAKI Hirotaka
Faculty of Bioresources, Mie University
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OHTA Rie
Biodevelopment Division, Central Institute, nagoya Seiraku Co., Ltd.
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ISHIKAWA Keiko
Biodevelopment Division, Central Institute, nagoya Seiraku Co., Ltd.
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Ohta Rie
Biodevelopment Division Central Institute Nagoya Seiraku Co. Ltd.
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Yoshida H
Division Of Food And Nutrition Nakamura Gakuen Junior College
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Ishikawa K
Biodevelopment Division Central Institute Nagoya Seiraku Co. Ltd.
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Yoshida Hiromi
Faculty Of Nutrition Kobe Gakuin University
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Fukuda Hiroyuki
Biodevelopment Division Central Institute Nagoya Seiraku Co. Ltd.
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Fukuda H
Choko Shoyu Miso Co‐op. Nagasaki Jpn
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Katsuzaki H
Faculty Of Bio-resources Mie University
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Fujino Tsuchiyoshi
Biodevelopment Division Central Institute Nagoya Seiraku Co. Ltd.
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Ishikawa Keiko
Biodevelopment Division, Central Institute, Nagoya Seiraku Co. Ltd.
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Katsuzaki Hirotaka
Faculty of Bio-resources, Mie University
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KATSUZAKI Hirotaka
Faculties of Bioresource, Mie University
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