Protective Effect of Ajoene on Acetaminophen-induced Hepatic Injury in Mice(Food & Nutrition Science)
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概要
- 論文の詳細を見る
Ajoene, a garlic-derived sulfur-containing compound, exhibited a hepatoprotective effect against acetaminophen-induced liver injury in mice. A pretreatment with ajoene suppressed the rise in serum glutamicpyruvic transaminase activity and the reduction in the hepatic reduced glutathione level. These effects of ajoene were observed dose-dependently (20-100 mg/kg). The pretreatment by ajoene also suppressed the decrease in hepatic protein thiol content resulting from acetaminophen administration.
- 社団法人日本農芸化学会の論文
- 2001-11-23
著者
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西川 俊夫
名古屋大学大学院生命農学研究科
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Hattori Atsuhiko
Biodevelopment Division Central Institute Nagoya Seiraku Co. Ltd.
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Hattori Atsuhiko
名古屋製酪
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YAMADA Norihiko
Biodevelopment Division, Central Institute, Nagoya Seiraku Co., Ltd.
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NISHIKAWA Tomoaki
Biodevelopment Division, Central Institute, Nagoya Seiraku Co., Ltd.
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FUKUDA Hiroyuki
Biodevelopment Division, Central Institute, Nagoya Seiraku Co., Ltd.
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FUJINO Tsuchiyoshi
Biodevelopment Division, Central Institute, Nagoya Seiraku Co., Ltd.
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Yamada Norihito
Department Of Nutrition Faculty Of Agriculture Tokyo University Of Agriculture
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Hattori Akihito
Biodevelopment Division Central Institute Nagoya Seiraku Co. Ltd.
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Fukuda Hiroyuki
Biodevelopment Division Central Institute Nagoya Seiraku Co. Ltd.
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Yamada Norihiko
Biodevelopment Division Central Institute Nagoya Seiraku Co. Ltd.
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Fujino Tsuchiyoshi
Biodevelopment Division Central Institute Nagoya Seiraku Co. Ltd.
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