An Organosulfur Compound Isolated from Oil-Macerated Garlic Extract, and Its Antimicrobial Effect
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概要
- 論文の詳細を見る
An organosulfur compound was isolated from oil-macerated garlic extract by silica gel column chromatography and preparative TLC. From the results of NMR, IR, and MS analyses, its structure was determined as E-4,5,9-trithiadeca-1,7-diene-9-oxide (iso-E-10-devinylajoene, iso-E-10-DA). This compound was different from E-4,5,9-trithiadeca-1,6-diene-9-oxide (E-10-devinylajoene, E-10-DA) only in the position of a double bond. Iso-E-10-DA had antimicrobial activity against Gram-positive bacteria, such as Bacillus cereus, B. subtilis, and Staphylococcus aureus, and yeasts at the concentration lower than 100μg/ml, but Gram-negative bacteria were not inhibited at the same concentration. The antimicrobial activity of iso-E-10-DA was inferior to those of similar oil-macerated garlic extract compounds such as E-ajoene, Z-ajoene, and Z-10-DA. From these results, it was suggested that trans structure and/or the position of double bond of iso-E-10-DA reduce the antimicrobial activity.
- 社団法人日本農芸化学会の論文
- 1999-03-23
著者
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YOSHIDA Hiroko
Division of Food and Nutrition, Nakamura Gakuen Junior College
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FUKUDA Hiroyuki
Biodevelopment Division, Central Institute, Nagoya Seiraku Co., Ltd.
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FUJINO Tsuchiyoshi
Biodevelopment Division, Central Institute, Nagoya Seiraku Co., Ltd.
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Suzuki Atsushi
Biodevelopment Division Central Institute Nagoya Seiraku Co. Ltd.
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Suzuki Atsushi
Department Of Applied Biological Chemistry Faculty Of Agriculture University Of Niigata
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Suzuki Atsushi
Synthetic Crystal Research Laboratory Faculty Of Engineering Nagoya University
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Suzuki Atsushi
Department Of Pathology Obstetrics And Gynecology Keio University School Of Medicine
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Suzuki Atsushi
Basic Research Department Prima Meat Packers Co. Ltd.
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Suzuki Atsushi
Department Of Applied Biochemistry Faculty Of Agriculture University Of Niigata
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Suzuki A
Department Of Obstetrics And Gynecology Keio University School Of Medicine
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Suzuki A
Department Of Applied Biological Chemistry Faculty Of Agriculture University Of Niigata
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YOSHIDA Hisae
Biodevelopment Division, Central Institute, nagoya Seiraku Co., Ltd.
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KATSUZAKI Hirotaka
Faculty of Bioresources, Mie University
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OHTA Rie
Biodevelopment Division, Central Institute, nagoya Seiraku Co., Ltd.
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ISHIKAWA Keiko
Biodevelopment Division, Central Institute, nagoya Seiraku Co., Ltd.
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Ohta Rie
Biodevelopment Division Central Institute Nagoya Seiraku Co. Ltd.
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Yoshida H
Division Of Food And Nutrition Nakamura Gakuen Junior College
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Ishikawa K
Biodevelopment Division Central Institute Nagoya Seiraku Co. Ltd.
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Yoshida Hiromi
Faculty Of Nutrition Kobe Gakuin University
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Fukuda Hiroyuki
Biodevelopment Division Central Institute Nagoya Seiraku Co. Ltd.
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Fukuda H
Choko Shoyu Miso Co‐op. Nagasaki Jpn
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Katsuzaki H
Faculty Of Bio-resources Mie University
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Fujino Tsuchiyoshi
Biodevelopment Division Central Institute Nagoya Seiraku Co. Ltd.
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Ishikawa Keiko
Biodevelopment Division, Central Institute, Nagoya Seiraku Co. Ltd.
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Katsuzaki Hirotaka
Faculty of Bio-resources, Mie University
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KATSUZAKI Hirotaka
Faculties of Bioresource, Mie University
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