Sesamol Induces Apoptosis in Human Lymphoid Leukemia Molt 4B Cells

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概要

• 論文の詳細を見る

• The exposure of human lymphoid leukemia Molt 4B cells to sesamol, a component of sesame oil led to both growth inhibition and the induction of apoptosis. Morphological change showing apoptotic bodies was observed in the cells treated with sesamol. The fragmentation of DNA by sesamol to oligonucleosomal-sized fragments that are characteristics of apoptosis was observed to be concentration- and time-dependent. On the other hand, in the sesamol-treated normal human lymphocytes morphological change and DNA fragmentation were not observed at all. These findings suggest that growth inhibition of Molt 4B cells by sesamol results from the induction of apoptosis in the cells.

• 社団法人　日本食品科学工学会の論文
• 2000-08-01

著者

• HIBASAMI Hiroshige

  Faculty of Medicine, Mie University

• Hibasami Hiroshige

  Faculty Of Medicine Mie University

• KATSUZAKI Hirotaka

  Faculty of Bioresources, Mie University

• Imai K

  Faculty Of Bio-resources Mie University

• Imai Kunio

  Faculty Of Bioresources Mie University

• Hirata Hitoshi

  Department Of Orthopaedic Surgery Mie University Faculty Of Medicine

• KOMIYA Takashi

  Faculty of Bioresources, Mie University

• Komiya T

  Mie Univ. Mie Jpn

• Komiya T

  Mie Univ. Mie

• Miyahara Yoshiyuki

  Kukisangyo Co. Ltd.

• Hibasami H

  Mie Univ. Mie Jpn

• Komiya Takashi

  Faculty Of Bio-resources Mie University

• Katsuzaki H

  Faculty Of Bio-resources Mie University

• Imai Kunio

  Faculty Of Bio-resources Mie University

• IMAI Kunio

  Faculties of Bioresources, Mie University

• Katsuzaki Hirotaka

  Faculty of Bio-resources, Mie University

• Hibasami Hiroshige

  Faculties of Medicine, Mie University

• KOMIYA Takashi

  Faculties of Bioresource, Mie University

• IMAI Kunio

  Faculties of Bioresource, Mie University

• KATSUZAKI Hirotaka

  Faculties of Bioresource, Mie University

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