Effect of Eucommiol Isolated from Aucuba (Aucuba japonica Thunb) on the Growth of Human Lymphoid Leukemia Cells

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概要

• 論文の詳細を見る

• We have investigated the effect of crude extract prepared from leaves of Japanese aucuba (Aucuba japonica Thunb) on the growth of human lymphoid leukemia Molt 4B cells. The extract suppressed the growth of these cells by 60% at the concentration of 200 μg/ml. Fraction III obtained by separation with HW40S gel chromatography inhibited the growth of the cells by 95% at the same concentration. We analyzed the structure of the compound contained in Fraction III, and identified it as eucommiol by NMR and MS. The antiproliferative effect of eucommiol on the growth of Molt 4B cells was examined, and it was found to moderately suppress the proliferation of Molt 4B cells by 41% at the concentration of 200 μg/ml.

• 社団法人　日本食品科学工学会の論文
• 1999-05-01

著者

• HIBASAMI Hiroshige

  Faculty of Medicine, Mie University

• Hibasami Hiroshige

  Faculty Of Medicine Mie University

• KATSUZAKI Hirotaka

  Faculty of Bioresources, Mie University

• Imai K

  Faculty Of Bio-resources Mie University

• Imai Kunio

  Faculty Of Bioresources Mie University

• Hirata Hitoshi

  Department Of Orthopaedic Surgery Mie University Faculty Of Medicine

• ACHIWA Yumiko

  Faculty of Obsterics and Gynecology, School of Medicine, Fujita Health University

• Achiwa Yumiko

  Faculty Of Bioresource Mie University

• KOMIYA Takashi

  Faculty of Bioresources, Mie University

• Komiya T

  Mie Univ. Mie Jpn

• Komiya T

  Mie Univ. Mie

• Hibasami H

  Mie Univ. Mie Jpn

• ISHII Yaeko

  Faculty of Medicine, Mie University

• YOSHIOKA Kazumi

  Faculty of Medicine, Mie University

• NAKANISHI Kimiko

  Faculty of Medicine, Mie University

• KOJIMA Teruko

  Faculty of Medicine, Mie University

• OHNISHI Kazuko

  Faculty of Medicine, Mie University

• Ishii Yaeko

  Faculty Of Medicine Mie University

• Kojima Teruko

  Faculty Of Medicine Mie University

• Ohnishi Kazuko

  Faculty Of Medicine Mie University

• Komiya Takashi

  Faculty Of Bio-resources Mie University

• Nakanishi Kimiko

  Faculty Of Medicine Mie University

• Yoshioka Kazumi

  Faculty Of Medicine Mie University

• Katsuzaki H

  Faculty Of Bio-resources Mie University

• Imai Kunio

  Faculty Of Bio-resources Mie University

• IMAI Kunio

  Faculties of Bioresources, Mie University

• Katsuzaki Hirotaka

  Faculty of Bio-resources, Mie University

• Hibasami Hiroshige

  Faculties of Medicine, Mie University

• KOMIYA Takashi

  Faculties of Bioresource, Mie University

• IMAI Kunio

  Faculties of Bioresource, Mie University

• KATSUZAKI Hirotaka

  Faculties of Bioresource, Mie University

• ACHIWA Yumiko

  Faculties of Bioresource, Mie University

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