Synthetic Search for Cosmetic Ingredients: Preparations, Tyrosinase Inhibitory and Antioxidant Actibities of Caffeic Amides
スポンサーリンク
概要
- 論文の詳細を見る
Six caffeic amides 1-6 were synthesized by condensing caffeic acid (CA) with serine or lysine derivatives. Tyrosinase inhibitory and antioxidant activities were measured to find effective cosmetic ingredients. Most of the derivatives prepared showed tyrosinase inhibition stronger than or comparable to CA, the amino acids, chlorogenic acid (CGA) or arbutin, and showed antioxidant activity stronger than the most popular whitening agents, kojic acid or arbutin. N-Caffeoyl-O-acetylserine methyl ester 3 showed the strongest activity in two assay systems and proved to be a promising candidate for cosmetic ingredients.
- 日本油化学会の論文
- 2002-01-01
著者
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Imai K
Faculty Of Bio-resources Mie University
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Imai Kunio
Laboratory Of Organic Chemistry Faculty Of Agriculture Nagoya University:(present Office)laboratory
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Imai Kunio
Faculty Of Bioresources Mie University
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Tada Takahiro
Faculty Of Bio-resources Mie University
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KOMIYA Takashi
Faculty of Bioresources, Mie University
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Komiya T
Mie Univ. Mie Jpn
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Komiya T
Mie Univ. Mie
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OHNISHI Kazuomi
Research & Development Department, Mikimoto Pharmaceutical Co., Ltd.
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Komiya Takashi
Faculty Of Bio-resources Mie University
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Ohnishi Kazuomi
Research & Development Department Mikimoto Pharmaceutical Co. Ltd.
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Imai Kunio
Faculty Of Bio-resources Mie University
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IMAI Kunio
Faculties of Bioresources, Mie University
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KOMIYA Takashi
Faculties of Bioresource, Mie University
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IMAI Kunio
Faculties of Bioresource, Mie University
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