Physico-chemical Properties of Fatty Acids for Assessing the Threshold Concentration to Enhance the Absorption of a Hydrophilic Substance
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概要
- 論文の詳細を見る
The effects of natural and non-natural fatty acids on enhancing the absorption of a hydrophilic marker through a human epithelial cell(Caco-2)monolayer were measured to elucidate the properties of the fatty acids.Fatty acids from C9 to C14 enhanced the absorption depending on the concentration and the carbon chain length.Those fatty acids with longer chains gave a higher permeability coefficient at low concentrations and a lower toxicity than those with shorter chains.The surface energy lowering coefficient(SELC), an intrinsic physico-chemical property, and the critical micellar concentration(CMC)were good criteria for identifying the threshold concentrations of a fatty acid to significantly enhance absorption.
- 社団法人日本農芸化学会の論文
- 1998-03-23
著者
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Kimura Yoshinobu
The International Center For Biotechnology Osaka University
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ADACHI Shuji
Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University
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Hosoda Yasuo
Division Of Applied Life Sciences Graduate School Of Agriculture Kyoto University
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Kimura Y
Department Of Biological And Environmental Chemistry Faculty Of Agriculture Tottori University
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Adachi S
Div. Of Food Sci. And Biotechnology Graduate School Of Agriculture Kyoto Univ.
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MATSUNO Ryuichi
Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University
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SHIMA Motohiro
Division of Food Science and Technology, Graduate School of Agriculture, Kyoto University
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Shima Motohiro
Division Of Applied Life Sciences Graduate School Of Agriculture Kyoto University
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KIMURA Yukitaka
Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University
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Matsuno R
Division Of Food Science And Biotechnology Graduate School Of Agriculture Kyoto University
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Hosoda Yoshisuke
Division Of Applied Life Sciences Graduate School Of Agriculture Kyoto University
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Kimura Yukitaka
Division Of Food Science And Biotechnology Graduate School Of Agriculture Kyoto University
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Adachi Shuji
Division Of Applied Life Sciences Graduate School Of Agriculture Kyoto University
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Matsuno Ryuichi
Division Of Applied Life Sciences Graduate School Of Agriculture Kyoto University
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