Effect of Neuroprotective Flavonoids of Agrimonia eupatoria on Glutamate-Induced Oxidative Injury to HT22 Hippocampal Cells

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概要

• 論文の詳細を見る

• A methanolic extract of Agrimonia eupatoria (Rosaceae) significantly attenuated glutamate-induced oxidative stress in HT22 hippocampal cells. A new flavonoid, characterized as kaempferol 3-O-β-D-(2″-O-acetyl-6″-(E)-p-coumaroyl)-glucopyranoside (2″-acetyl-tiliroside (1), was isolated from the methanolic extract of A. eupatoria stems together with nine known flavonoids. Compounds 4, 7, 8 and 9 all showed a neuroprotective effect on glutamate-induced toxicity in HT22 cells.

• 社団法人 日本農芸化学会の論文
• 2010-08-23

著者

• Kim Young

  College of Pharmacy, Chungnam National University

• Sung Sang

  College of Pharmacy, Seoul National University

• Kim Seung

  College of Bioscience and Biotechnology, Department of Biomaterials Engineering, Kangwon National Un

• Kim Yun

  Colledge Of Pharmacy Wonkwang University

• Kim Youn

  韓国

• Jeong Eun

  Coll. Of Pharmacy And Res. Inst. Of Pharmaceutical Sci. Seoul National Univ.

• Kim Young

  Department Of Physiology And Biophysics Seoul National University College Of Medicine

• LEE Ki

  College of Pharmacy, Seoul National University

• Kim Young

  College Of Pharmacy And Research Institute Of Pharmaceutical Science Seoul National University

• Kim S

  National Institute Of Toxicological Research Korea Food And Drug Administration

• Lee Ki

  Coll. Of Pharmacy And Res. Inst. Of Pharmaceutical Sci. Seoul National Univ.

• Sung S

  Seoul National Univ. Seoul Kor

• Kim Young

  Coll. Of Pharmacy And Res. Inst. Of Pharmaceutical Sci. Seoul National Univ.

• Kim Y

  Coll. Of Pharmacy And Res. Inst. Of Pharmaceutical Sci. Seoul National Univ.

• HWANG Lim

  College of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University

• JEONG Eun

  College of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University

• Lee Ki

  College Of Pharmacy And Research Institute Of Pharmaceutical Science Seoul National University

• Hwang Lim

  College Of Pharmacy And Research Institute Of Pharmaceutical Science Seoul National University

• Jeong Eun

  College Of Pharmacy And Research Institute Of Pharmaceutical Science Seoul National University

• Sung Sang

  College Of Pharmacy Seoul National University

• Sung Sang

  College Of Pharmacy And Research Institute Of Pharmaceutical Science Seoul National University

• Kim Young

  Colledge of Pharmacy, Wonkwang University

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