Oleanane Triterpenoids with Inhibitory Activity against NFAT Transcription Factor from Liquidambar formosana (Pharmacognosy)

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概要

• 論文の詳細を見る

• In a search for inhibitory components from natural products against NFAT transcription factor, this study investigated the ethyl acetate extract of the fruits of Liquidambar formosana. Four oleanane triterpenoids were isolated and identified to be liquidambaric acid, oleanolic acid, 3α-acetoxy-25-hydroxy-olean-12-en-28-oic acid and lantanolic acid. Of these compounds, 3α-acetoxy-25-hydroxy-olean-12-en-28-oic acid (IC_<50> : 4.63 μM) and lantanolic acid (IC_<50> : 12.62 μM) exhibited strong inhibitory activity against the NFAT transcription factor.

• 公益社団法人日本薬学会の論文
• 2004-03-01

著者

• Kim Young

  College of Pharmacy, Chungnam National University

• Kwon Young-in

  Dep. Of Food And Nutrition Hannam Univ.

• Kim Young

  Coll. Of Pharmacy Chungnam National Univ.

• CAI Xing

  College of Pharmacy, Chungnam National University

• Lee I

  College Of Pharmacy Chungnam National University

• Dat N

  College Of Pharmacy Chungnam National University

• Dat Nguyen

  College Of Pharmacy Chungnam National University

• Cai X

  College Of Pharmacy Chungnam National University

• Cai Xing

  College Of Pharmacy Chungnam National University

• Kim Y

  College Of Pharmacy Chungnam National University

• Kim Young

  Korea University

• Kim Young

  College Of Pharmacy And Research Institute Of Pharmaceutical Science Seoul National University

• Cai Xing

  Korea Res. Inst. Of Bioscience And Biotechnology Kor

• Lee Im

  College Of Pharmacy Chungnam National University

• SHEN Guanghai

  College of Pharmacy, Chungnam National University

• Shen Guanghai

  College Of Pharmacy Chungnam National University

• Lee I

  Korea Res. Inst. Biosci. And Biotechnol. Taejon Kor

• Kim Young

  Colledge of Pharmacy, Wonkwang University

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