Total Peroxynitrite Scavenging Capacity of Phenylethanoid and Flavonoid Glycosides from the Flowers of Buddleja officinalis
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概要
- 論文の詳細を見る
Nine compounds, including six phenylethanoid glycosides: acteoside (1); bioside (2); echinacoside (3); poliumoside (4); phenylethyl glycoside (5); salidroside (6) and three flavonoids; linarin (7); apigenin (8); isorhoifolin (9), were isolated from the flowers of Buddleja officinalis MAXIM. (Buddlejaceae). Chemical structures were confirmed by 1H-, and 13C-NMR, and MS spectral methods and compared with those reported in the literature. Antioxidant activities of the methanol and water extracts, and all isolated compounds were evaluated using the total oxidant scavenging capacity (TOSC) assay against peroxynitrite. Results of the assay showed that the phenylethanoid glycosides, a major class of compounds of the flowers of B. officinalis, possess strong antioxidant activity. Of these, acteoside, echinacoside and poliumoside have 9.9-, 9.8- and 9.5-fold TOSC value, respectively, compared with the positive control, Trolox.
- 公益社団法人 日本薬学会の論文
著者
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TUNG Nguyen
College of Pharmacy, Chungnam National University
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Kim Jeong
College of Oriental Medicine, Kyung Hee University
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Cuong Nguyen
Institute Of Chemistry Vietnamese Academy Of Science And Technology
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Kim Sang
College Of Pharmacy Seoul National University
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Nhiem Nguyen
College of Pharmacy, Chungnam National University
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Tai Bui
Institute of Marine Biochemistry, Vietnam Academy of Science and Technology
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Kim Young
College Of Pharmacy And Research Institute Of Pharmaceutical Science Seoul National University
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Huong Tran
Institute of Natural Products Chemistry, Vietnam Academy of Science and Technology
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Jung Bong
College of Pharmacy, Chungnam National University
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Linh Pham
Institute of Chemistry, VAST
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Anh Ngo
Institute of Natural Products Chemistry, VAST
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Cuong Nguyen
Institute Of Archeology
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Kim Young
Colledge of Pharmacy, Wonkwang University
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Tai Bui
Institute of Natural Products Chemistry, VAST
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Kim Jeong
College of Pharmacy, Chungnam National University
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Huong Tran
Institute of Natural Products Chemistry, VAST
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Kim Sang
College of Pharmacy, Chungnam National University
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