Ursolic Acid Enhances Cyclooxygenases and Tumor Necrosis Factor-α Expression in Mouse Skin

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概要

• 論文の詳細を見る

• An anti-inflammatory triterpenoid, ursolic acid (UA), has recently been found unexpectedly to induce the release of a pro-inflammatory mediator in resting macrophages. In this study, we found that topical applications of UA to mouse skin twice a week for 2 weeks significantly enhanced mRNA expression of cyclooxygenase (COX)-1, COX-2, and tumor necrosis factor-α, whereas its effect on tumor promotion was unclear.

• 社団法人 日本農芸化学会の論文
• 2006-04-23

著者

• MURAKAMI Akira

  Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University

• OHIGASHI Hajime

  Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University

• Ohigashi Hajime

  京都大学 農学研究科食品生物科学

• Ohigashi Hajime

  Division Of Applied Life Sciences Graduate School Of Agriculture Kyoto University

• IKEDA Yasutaka

  Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University

• NISHIZAWA Takashi

  Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University

• Murakami Akira

  Division Of Food Science And Biotechnology Graduate School Of Agriculture Kyoto University

• Nishizawa Takashi

  Division Of Food Science And Biotechnology Graduate School Of Agriculture Kyoto University

• Ikeda Yasutaka

  Division Of Food Science And Biotechnology Graduate School Of Agriculture Kyoto University

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