Inhibition by Genistein of the Lipopolysaccharide-Induced Down-Regulation of Programmed Cell Death 4 in RAW 264.7 Mouse Macrophages
スポンサーリンク
概要
- 論文の詳細を見る
Programmed cell death 4 (Pdcd4), a novel tumor suppressor, has recently emerged as an anti-inflammatory protein. We assessed in the present study the effects of 18 different food factors with anti-inflammatory activity on the lipopolysaccharide-induced down-regulation of pdcd4 mRNA expression in mouse RAW 264.7 macrophages. Genistein, a soy isoflavone, significantly inhibited pdcd4 down-regulation.
- 社団法人 日本農芸化学会の論文
著者
-
MURAKAMI Akira
Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University
-
IRIE KAZUHIRO
Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University
-
YASUDA Michiko
Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University
関連論文
- Lack of Enhancing Effect of Lauric Acid on the Development of Aberrant Crypt Foci in Male ICR Mice Treated with Azoxymethane and Dextran Sodium Sulfate
- Combinatorial Effects of Nonsteroidal Anti-inflammatory Drugs and Food Constituents on Production of Prostaglandin E_2 and Tumor Necrosis Factor-α in RAW264.7 Murine Macrophages(Food & Nutrition Science)
- Suppression of N-Nitrosomethylbenzylamine-induced Rat Esophageal Tumorigenesis by Dietary Feeding of 1'-Acetoxychavicol Acetate.
- Anti-tumor Promoting Activity of Bufadienolides from Kalanchoe pinnata and K.daigremontiana×tubiflora
- In Vitro Absorption and Metabolism of Nobiletin, a Chemopreventive Polymethoxyflavonoid in Citrus Fruits
- An Avocado Constituent, Persenone A, Suppresses Expression of Inducible Forms of Nitric Oxide Synthase and Cyclooxygenase in Macrophages, and Hydrogen Peroxide Generation in Mouse Skin
- Inhibition by (-)-Persenone A-related Compounds of Nitric Oxide and Superoxide Generation from Inflammatory Leukocytes
- Immunomodulatory Action of Citrus Auraptene ton Macrophage Functions and Cytokine Production of Lymphocytes in Female BALB/c Mice.
- Suppression of N-Nitrosomethylbenzylamine-induced Rat Esophageal Tumorigenesis by Dietary Feeding of 1'-Acetoxychavicol Acetate
- Screening for the In Vitro Anti-tumor-promoting Activities of Edible Plants from Malaysia
- Identification of Zerumbone in Zingiber zerumbet Smith as a Potent Inhibitor of 12-O-Tetradecanoylphorbol-13-acetate-induced Epstein-Barr Virus Activation
- Citrus Auraptene Exerts Dose-dependent Chemopreventive Activity in Rat Large Bowel Tumorigenesis : The Inhibition Correlates with Suppression of Cell Proliferation and Lipid Peroxidation and with Induction of Phase II Drug-me
- Citrus Auraptene Inhibits Chemically Induced Colonic Aberrant Crypt Foci in Male F344 Rats.
- Chemoprevention of Azoxymethane-induced Rat Colon Carcinogenesis by a Xanthine Oxidase Inhibitor, 1'-Acetoxychavicol Acetate.
- A Xanthine Oxiedase Inhibitor 1'-Acetoxychavicol Acetate Inhibits Azoxymethane-induced Colonic Aberrant Crypt Foci in Rats.
- Inhibitory Effects of Curcumin and Tetrahydrocurcuminoids on the Tumor Promoter-induced Reactive Oxygen Species Generation in Leukocytes in vitro and in vivo
- Chemoprevention of Azoxymethane-induced Rat Colon Carcinogenesis by a Xanthine Oxidase Inhibitor, 1'-Acetoxychavicol Acetate
- Chemopreventive Effect of a Xanthine Oxidase Inhibitor, l'-Acetoxychavicol Acetate, on Rat Oral Carcinogenesis.
- Auraptene, a Citrus Coumarin, Inhibits 12-O-Tetradecanoylphorbol-13-acetate-induced Tumor Promotion in ICR Mouse Skin, Possibly through Suppression of Superoxide Generation in Leukocytes
- Identitication of Pheophorbide a and Its Related Compounds as Possible Anti-tumor Promoters in the Leaves of Neptunia oleracea
- Chemopreventive Effect of a Xanthine Oxidase Inhibitor, 1'-Acetoxychavicol Acetate, on Rat Oral Carcinogenesis
- Structure of β-Amyloid Fibrils and Its Relevance to Their Neurotoxicity : Implications for the Pathogenesis of Alzheimer's Disease
- Synthesis and Tumor-promoting Activities of 12-Epi-phorbol-12,13-dibutyrate
- Synthesis and Biological Activities of (-)-6-n-Octyl-indolactam-V, a New Potent Analogue of the Tumor Promoter (-)-Indolactam-V
- Synthesis and Biological Activities of Indolactone-V, the Lactone Analogue of the Tumor Promoter (-)-Indolactam-V
- Inhibitory Effects of 1'-Acetoxychavicol Acetate on N-Nitrosobis(2-oxopropyl)-amine-induced Initiation of Cholangiocarcinogenesis in Syrian Hamsters
- Possible Anti-tumor Promoting Properties of Edible Plants from Thailand, and Identification of an Active Constituent, Cardamonin, of Boesenbergia pandurata
- Suppressive Effects of Natural and Synthetic Agents on Dextran Sulfate Sodium-induced Interleukin-1β Release from Murine Peritoneal Macrophages
- Ursolic Acid Enhances Cyclooxygenases and Tumor Necrosis Factor-α Expression in Mouse Skin
- Suppressive Effects of Selected Antioxidants on the Activated Leukocytes-induced Mutagenesis in the Co-culture Assay Systems
- Modifying Effects of Dietary Factors on (−)-Epigallocatechin-3-gallate-induced Pro-matrix Metalloproteinase-7 Production in HT-29 Human Colorectal Cancer Cells
- Auraptene Decreases the Activity of Matrix Metalloproteinases in Dextran Sulfate Sodium-Induced Ulcerative Colitis in ICR Mice
- Nobiletin, a Citrus Flavonoid, Down-Regulates Matrix Metalloproteinase-7 (matrilysin) Expression in HT-29 Human Colorectal Cancer Cells
- 1'-Acetoxychavicol Acetate as a Potent Inhibitor of Tumor Promoter-induced Epstein-Barr Virus Activation from Languas galanga, a Traditional Thai Condiment
- Binding Selectivity of Conformationally Restricted Analogues of (-)-Indolactam-V to the C1 Domains of Protein Kinase C Isozymes(Organic Chemistry)
- Isolation of (-)-14-O-Malonylindolactam-V as a Possible Precursor of (-)-Indolactam-V and (-)-14-O-Acetylindolactam-V from Streptomyces blastmyceticum
- Tumor-Promoting Phorbol Esters Bind Directly to the Regulatory Domain of Diacylglycerol Kinase Gamma
- Anti-tumor Promotion with Food Phytochemicals: A Strategy for Cancer Chemoprevention
- Synthesis and Phorbol Ester Binding of the Zinc-finger Like Sequences of All Protein Kinase C Isozymes
- Inhibition by Genistein of the Lipopolysaccharide-Induced Down-Regulation of Programmed Cell Death 4 in RAW 264.7 Mouse Macrophages
- Identification of Toxic Conformation in Aβ42 Aggregates Using Solid-state NMR
- Possible Inhibitor of Tumor Promotion and Related Polyphenol from Lophira alata, a Medicinal Plant in Tropical West Africa(Organic Chemistry)
- In Vitro Covalent Binding Proteins of Zerumbone, a Chemopreventive Food Factor
- In Vitro Covalent Binding Proteins of Zerumbone, a Chemopreventive Food Factor
- Inhibition by Genistein of the Lipopolysaccharide-Induced Down-Regulation of Programmed Cell Death 4 in RAW 264.7 Mouse Macrophages
- Silymarin Attenuated the Amyloid β Plaque Burden and Improved Behavioral Abnormalities in an Alzheimer's Disease Mouse Model
- The turn formation at positions 22 and 23 in the 42-mer amyloid β peptide : The emerging role in the pathogenesis of Alzheimer's disease
- Verification of the Intermolecular Parallel β-Sheet in E22K-Aβ42 Aggregates by Solid-State NMR Using Rotational Resonance : Implications for the Supramolecular Arrangement of the Toxic Conformer of Aβ42
- Chalcone Tetramers, Lophirachalcone and Alatachalcone, from Lophira alata as Possible Anti-tumor Promoters
- Silymarin Attenuated the Amyloid β Plaque Burden and Improved Behavioral Abnormalities in an Alzheimer’s Disease Mouse Model
- Synthesis and Biological Evaluation of the 12,12-Dimethyl Derivative of Aplog-1, an Anti-Proliferative Analog of Tumor-Promoting Aplysiatoxin