Amylomyces rouxii Strain CBS 438.76 Affects Cholesterol Metabolism in Cholesterol-Fed Rats
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概要
- 論文の詳細を見る
We examined the effects of Amylomyces rouxii, which is a mold found in some fermented foods in Indonesia, on serum cholesterol and hepatic LDL receptor mRNA in rats. Rats were fed a 0.5% cholesterol-enriched diet with (A. rouxii group) or without (control group) 30 g/kg A. rouxii for 4 wk. There were no significant differences in the body weight, food intake or liver weight among the groups. However, the weight of the cecum in the A. rouxii-fed group was significantly higher than that in the control group. The cecal pH in the A. rouxii-fed group was significantly lower than that in the control group. Cecal acetic acid, propionic acid and total SCFA concentrations in the A. rouxii-fed group were significantly higher than those in the control group. The serum total cholesterol and VLDL+intermediate density lipoprotein (IDL)+LDL-cholesterol concentrations in the control group were significantly higher than those in the A. rouxii-fed group at the end of the 4-wk feeding period. There were no significant differences in the HDL-cholesterol or triglyceride concentrations between the groups. The hepatic LDL receptor and cholesterol 7α-hydroxylase mRNA levels in the A. rouxii-fed group were significantly higher than those in the control group. The results of this study demonstrate that feeding of A. rouxii lowers the serum total cholesterol level by enhancement of the cecal SCFA concentration and the hepatic LDL receptor mRNA.
- 日本ビタミン学会の論文
著者
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ODA Yuji
Department of Food Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro
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Han Kyu-ho
農業･食品産業技術総合研究機構北海道農業研究センター 北海道畑輪作研究チーム
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Han Kyu-ho
岩手大学 大学院連合農学研究科
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Han Kyu-ho
Department Of The Electronics Engineering The Korea University
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FUKUSHIMA Michihiro
Department of Agricultural and Life Science, Obihiro University of Agriculture and Veterinary Medici
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IIJIMA Setsuko
Department of Food Science, Obihiro University of Agriculture and Veterinary Medicine
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SHIMADA Ken-ichiro
Department of Food Science, Obihiro University of Agriculture and Veterinary Medicine
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SEKIKAWA Mitsuo
Department of Food Science, Obihiro University of Agriculture and Veterinary Medicine
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CHIJI Hideyuki
Department of Food Science and Human Nutrition, Faculty of Human Ecology, Fuji Women's College
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島田 謙一郎
帯広畜産大学畜産科学科
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Shimada Ken-ichiro
Graduate School Of Global Information And Telecommunications Studies Waseda University
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Sekikawa Mitsuo
Dep. Of Animal Sci. Obihiro Univ. Of Agriculture And Veterinary Medicine
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Sekikawa Mitsuo
Department Of Agriculture And Life Science Obihiro University Of Agriculture And Veterinary Medicine
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Oda Yuji
Department Of Upland Agriculture National Agricultural Research Center For Hokkaido Region
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Chiji Hideyuki
Department Of Food Science And Human Nutrition Faculty Of Human Ecology Fuji Women's College
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Chiji Hideyuki
Department Of Agricultural Chemistry Faculty Of Agriculture Hokkaido University
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TANEICHI Yae
Department of Animal Science, Obihiro University of Agriculture and Veterinary Medicine
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SAITOH Katsuichi
Department of Upland Agriculture, National Agricultural Research Center for Hokkaido Region
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Shimada Kenichiro
Department Of Food Science Obihiro University Of Agriculture And Veterinary Medicine
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Taneichi Yae
Department Of Animal Science Obihiro University Of Agriculture And Veterinary Medicine
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Iijima Setsuko
Department Of Animal Science Obihiro University Of Agriculture And Veterinary Medicine
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Shimada Ken-ichiro
Department Of Food Science Obihiro University Of Agriculture And Veterinary Medicine
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Han Kyu-ho
Department Of Food Science Obihiro University Of Agriculture And Veterinary Medicine
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Oda Yuji
Department Of Agricultural And Life Science Obihiro University Of Agriculture And Veterinary Medicin
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Fukushima Michihiro
Department Of Food Science Obihiro University Of Agriculture And Veterinary Medicine
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Saitoh Katsuichi
Department Of Upland Agriculture National Agricultural Research Center For Hokkaido Region
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Sekikawa Mistuo
Department Of Animal And Food Hygiene Obihiro University Of Agriculture And Veterinary Medicine
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HAN Kyu-Ho
Department of Animal Science, Obihiro University of Agriculture and Veterinary Medicine
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SHIMADA Ken-ichiro
Department of Animal Science, Obihiro University of Agriculture and Veterinary Medicine
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