Cholesterol Metabolism in Rat Is Affected by Protocatechuic Acid
スポンサーリンク
概要
- 論文の詳細を見る
The effects of protocatechuic acid on serum cholesterol and gene expression related to cholesterol metabolism in rats were investigated. Rats were fed a cholesterol-free diet with or without 5 g protocatechuic acid/kg diet for 4 wk. There were no significant differences in body weight and food intake among groups through the experimental period. The liver weight in the protocatechuic acid group was significantly lower than that in the control group. The serum total cholesterol, high-density lipoprotein (HDL)-cholesterol and very low-density lipoprotein (VLDL)+intermediate density lipoprotein (IDL)+low-density lipoprotein (LDL)-cholesterol concentrations in the protocatechuic acid group were significantly lower than those in the control group through the feeding period. The hepatic cholesterol concentration in the protocatechuic acid group was significantly higher than in the control group at the end of the 4-wk feeding period. The relative hepatic LDL receptor, apo B, apo E, lecithin-cholesterol acyltransferase (LCAT) and hepatic triglyceride lipase (HTGL) mRNA levels in the protocatechuic acid group were significantly higher than those in the control group. The results of this study suggest the possibility that the increase in the hepatic LDL receptor, apo E, LCAT and HTGL guessed by these mRNAs increase in the protocatechuic acid group lowers the serum total cholesterol level.
- 日本ビタミン学会の論文
著者
-
Han Kyu-ho
農業･食品産業技術総合研究機構北海道農業研究センター 北海道畑輪作研究チーム
-
Han Kyu-ho
岩手大学 大学院連合農学研究科
-
Han Kyu-ho
Department Of The Electronics Engineering The Korea University
-
FUKUSHIMA Michihiro
Department of Agricultural and Life Science, Obihiro University of Agriculture and Veterinary Medici
-
SHIMADA Ken-ichiro
Department of Food Science, Obihiro University of Agriculture and Veterinary Medicine
-
SEKIKAWA Mitsuo
Department of Food Science, Obihiro University of Agriculture and Veterinary Medicine
-
Nakano M
Department Of Animal Science Obihiro University Of Agriculture And Veterinary Medicine
-
Nakano Masuo
Department Of Bioresource Science Obihiro University Of Agriculture & Veterinary Medicine
-
CHIJI Hideyuki
Department of Food Science and Human Nutrition, Faculty of Human Ecology, Fuji Women's College
-
TAMURA Akiko
Department of Animal Science, Obihiro University of Agriculture and Veterinary Medicine
-
WATANABE Shoko
Department of Animal Science, Obihiro University of Agriculture and Veterinary Medicine
-
MATSUMOTO Megumi
Department of Food Science and Human Nutrition, Faculty of Human Life Science, Fuji Women's Universi
-
Tamura Akiko
Res. Inst. Fancl Co.
-
Tamura Akiko
Obihiro Univ. Agriculture And Veterinary Medicine Hokkaido Jpn
-
島田 謙一郎
帯広畜産大学畜産科学科
-
Nakano Masuo
Department Of Agro-environmental Science Obihiro University Of Agriculture And Veterinary Medicine
-
Sekikawa Mitsuo
Dep. Of Animal Sci. Obihiro Univ. Of Agriculture And Veterinary Medicine
-
Sekikawa Mitsuo
Department Of Agriculture And Life Science Obihiro University Of Agriculture And Veterinary Medicine
-
Chiji Hideyuki
Department Of Food Science And Human Nutrition Faculty Of Human Ecology Fuji Women's College
-
Chiji Hideyuki
Department Of Agricultural Chemistry Faculty Of Agriculture Hokkaido University
-
Matsumoto Megumi
Department Of Food And Nutrition Sciences Graduate School Of Dairy Science Research Rakuno Gakuen Un
-
Matsumoto Megumi
Department Of Food Science And Human Nutrition Faculty Of Human Life Science Fuji Women's Unive
-
Shimada Ken-ichiro
Department Of Food Science Obihiro University Of Agriculture And Veterinary Medicine
-
Watanabe Shoko
Department Of Animal Science Obihiro University Of Agriculture And Veterinary Medicine
-
Han Kyu-ho
Department Of Food Science Obihiro University Of Agriculture And Veterinary Medicine
-
Fukushima Michihiro
Department Of Food Science Obihiro University Of Agriculture And Veterinary Medicine
-
Sekikawa Mistuo
Department Of Animal And Food Hygiene Obihiro University Of Agriculture And Veterinary Medicine
-
HAN Kyu-Ho
Department of Animal Science, Obihiro University of Agriculture and Veterinary Medicine
-
SHIMADA Ken-ichiro
Department of Animal Science, Obihiro University of Agriculture and Veterinary Medicine
関連論文
- The effects of di-D-fructofuranose-1,2':2,3'-dianhydride (DFA III) administration on human intestinal microbiota.
- 骨付き生ハムの製造とその微生物学的および理化学的性質
- Effects of High-Molecular-Weight Glutenin Subunits on the Texture of Yellow Alkaline Noodles Using Near-Isogenic Lines
- Staling and Texture of Bread Prepared from New Japanese Bread Wheat Varieties with Slightly Low-Amylose Starch
- 7. 定量的RT-PCR解析を用いたコレステロール負荷ラットにおけるn-6およびn-3脂肪酸食の長期投与がコレステロール代謝に関連するmRNA発現に及ぼす影響
- Effect of White Wheat Bread Containing Sugar Beet Fiber on Serum Lipids and Hepatic mRNA in Rats Fed on a Cholesterol-Free Diet
- Prehistoric Sado Island Populations of Sus scrofa Distinguished from Contemporary Japanese Wild Boar by Ancient Mitochondrial DNA
- Ancient DNA Reveals Genetic Lineage of Sus scrofa among Archaeological Sites in Japan
- Variations in Mitochondrial DNA of Dogs from Archaeological Sites in Japan and NeighbouringIslands
- Genetic Variation of the Mitochondrial DNA Cytochrome b Region in Japanese Native Dog Breeds (Canis familiaris)(Genetics)
- Hepatoprotective Effects of the Water Extract from Adzuki Bean Hulls on Acetaminophen-Induced Damage in Rat Liver
- Cholesterol Metabolism in Rat Is Affected by Protocatechuic Acid
- Resistant Starches of Beans Reduce the Serum Cholesterol Concentration in Rats
- Investigation of Gene Expressions Related to Cholesterol Metabolism in Rats Fed Diets Enriched in n-6 or n-3 Fatty Acid with a Cholesterol after Long-term Feeling Using Quantitative-competitive RT-PCR Analysis
- Effects of a Probiotic on the Lipid Metabolism of Cocks Fed on a Cholesterol-enriched Diet
- A Mixture of Organisms Affects Cholesterol Metabolism Together with Rat Cecal Flora
- Comparative Hypocholesterolemic Effects of Five Animal Oils in Cholesterol-fed Rats
- Oxidation of Triacylglycerol by Laccase-Natural Mediator and Laccase-Mediator Derived from Natural Compound Systems
- Effect of Shellfish Calcium on the Apparent Absorption of Calcium and Bone Metabolism in Ovariectomized Rats
- Effect of an Adzuki Bean Extract on Hepatic Anti-Oxidant Enzyme mRNAs in D-Galactosamine-Treated Rats
- Fat- and Cholesterol-Enriched Diet Feeding Affects Gene Expression Related to Cholesterol Metabolism in Rats
- Effects of Food Additives on Susceptibility of Gram Negative Bacteria Derived from Dry-Fermented Sausage
- Calcium Bioavailability of a Total Bone Extract (TBE) and Its Effects on Bone Metabolism in Rats
- Influence of a Probiotic on Productivity, Meat Components, Lipid Metabolism, Caecal Flora and Metabolites, and Raising Environment in Broiler Production
- Influence of a Probiotic on Productivity, Meat Components, Lipid Metabolism, Caecal Flora and Metabolites, and Raising Environment in Broiler Production
- Distribution of PCDDs/PCDFs and Co-PCBs in Human Maternal Blood, Cord Blood, Placenta, Milk, and Adipose Tissue : Dioxins Showing High Toxic Equivalency Factor Accumulate in the Placenta
- Effects of the Lipid-Saccharide Complex and Unsaponifiable Matter from Sunflowers on Liver Lipid Metabolism and Intestinal Flora in Rats
- Phylogeography and Population Structure of the Japanese Wild Boar Sus scrofa leucomystax : Mitochondrial DNA Variation(Animal Diversity and Evolution)
- Kinetic Changes in Free Ceramide and Cerebroside during Germination of Black Gram(Biological Chemistry)
- Structural Characterization of Triacylglycerol in Several Oils Containing Gamma-linolenic Acid(Food & Nutrition Science)
- Effects of Sunflowers on Lipid Metabolism in Rats
- Comparative Effect of Repeated Ingestion of Difructose Anhydride III and Palatinose on the Induction of Gastrointestinal Symptoms in Humans
- Evidence Suggesting That Difructose Anhydride III Is an Indigestible and Low Fermentable Sugar during the Early Stages after Ingestion in Humans
- A Localized Route Discovery for On-Demand Routing Protocols in Event-Driven Wireless Sensor Networks(Network)
- Supplementation of difructose anhydride III enhanced elevation of plasma equol concentrations and lowered plasma total cholesterol in isoflavone-fed rats.
- Difructose Anhydride III Does Not Contribute to Body Energy Accumulation in Rats
- Intestinal absorption and metabolism of a soluble flavonoid, alphaG-rutin, in portal cannulated rats.
- A soluble flavonoid-glycoside, alphaG-rutin, is absorbed as glycosides in the isolated gastric and intestinal mucosa.
- Absorptive activity of calcium in the isolated cecal epithelium adaptively increased by 2 week's feeding of difructose anhydride III in rats.
- Long-term oral administration of cows' milk improves insulin sensitivity in rats fed a high-sucrose diet
- Voluntary Running Exercise Alters Microbiota Composition and Increases n-Butyrate Concentration in the Rat Cecum
- An Efficient Routing Optimization Scheme Using Proxy Home Router(Network)
- 画像解析によるホルスタイン種を用いたBMSナンバー推定法ならびに異なる横断面の脂肪交雑特徴量の比較
- Web Based Student Testing System and its Test Results on Understanding of Scotland History Subjects
- Web Based Student Testing System and its Test Results on Understanding of Scotland History Subjects
- Web Based Student Testing System and its Test Results on Understanding of Scotland History Subjects
- Red Potato Extract Protects from D-Galactosamine-induced Liver Injury in Rats
- Potato Pulps Lowered the Serum Cholesterol and Triglyceride Levels in Rats
- Hepatoprotective Effects of Purple Potato Extract against D-Galactosamine-Induced Liver Injury in Rats
- Potato and Soy Peptide Diets Modulate Lipid Metabolism in Rats
- Tartary Buckwheat Sprout Powder Lowers Plasma Cholesterol Level in Rats
- Anthocyanin-Rich Red Potato Flakes Affect Serum Lipid Peroxidation and Hepatic SOD mRNA Level in Rats
- Amylomyces rouxii Strain CBS 438.76 Affects Cholesterol Metabolism in Cholesterol-Fed Rats
- Molecular Species of Triacylglycerol Isolated from Depot Fats of Ratites
- 豚肉発酵調味料"肉醤"の性質
- DPPH Radical Scavengers from Dried Leaves of Oregano(Origanum vulgare)(Organic Chemistry)
- Improvement of Bone Strength and Dermal Thickness Due to Dietary Edible Bird’s Nest Extract in Ovariectomized Rats
- 非加熱食肉製品(生ハム)
- 帯広畜産大学畜産科学科畜肉保蔵学研究室における研究成果
- 乾塩ハム(ウリカリップハム)の製造とその性質
- Multiple Sclerosis Following Splenectomy as a Treatment for Idiopathic Thrombocytopenic Purpura
- Metaiodobenzylguanidine (MIBG) uptake in Parkinson's disease also decreases at thyroid
- REEXAMINATION OF DIRECT PREPARATION OF AMINO ACIDS FROM GLYCINE VIA N-SALICYLIDENEGLYCINATOAQUOCOPPER (Ⅱ)
- Substance P Immunoreactivity in the Rat Adrenal Gland during Postnatal Development(Anatomy)
- Immunohistochemical features of substance P-immunoreactive chromaffin cells and nerve fibers in the rat adrenal gland
- Oxidation of Triacylglycerol by Laccase-Mediator Systems
- Plastic casts and confocal laser scanning microscopy applied to the observation of enamel tubules in the red Kangaroo (Macropus rufus)
- Effects of judgement process on motor evoked potentials in Go/No-go hand movement task
- Intracerebral interactions caused by bilateral median nerve stimulation in man: a magnetoencephalographic study
- Ingestion of Gelatinized Potato Starch Containing a High Level of Phosphorus Decreases Serum and Liver Lipids in Rats
- Ingestion of Difructose Anhydride III Enhances Absorption and Retention of Calcium in Health Men
- Magnetoencephalographic study of intracerebral interactions caused by bilateral posterior tibial nerve stimulation in man
- Correlation between the Presence of Ubiquitin Conjugated Protein Phosphatase Inhibitor 1 and Postmortem Muscle Glycogen Metabolism
- Potato and Soy Peptide Diets Modulate Lipid Metabolism in Rats
- Voluntary Running Exercise Alters Microbiota Composition and Increases n-Butyrate Concentration in the Rat Cecum
- Effect of White Wheat Bread Containing Sugar Beet Fiber on Serum Lipids and Hepatic mRNA in Rats Fed on a Cholesterol-Free Diet
- Effect of Fermented Bean Paste on Serum Lipids in Rats Fed a Cholesterol-Free Diet
- Anthocyanin-Rich Red Potato Flakes Affect Serum Lipid Peroxidation and Hepatic SOD mRNA Level in Rats
- PCR-DGGE analysis of bacterial communities in funazushi, fermented crucian carp with rice, during fermentation
- 機能性糖質の研究の動向について : とくに機能性糖質のプレバイオティクス効果について
- Brain responses for the subconscious recognition of faces
- High Biliary Excretion Levels of Quercetin Metabolites after Administration of a Quercetin Glycoside in Conscious Bile Duct Cannulated Rats
- N-isopropyl-p- 123I Iodoamphetamine Single Photon Emission Computed Tomography Study of Parkinson’s Disease with Dementia
- Improvement of Bone Strength and Dermal Thickness Due to Dietary Edible Bird's Nest Extract in Ovariectomized Rats
- Hepatic Cytochrome P450 2E1 Level Rather Than Cecal Condition Contributes to Induction of Early Stage of the Alcoholic Liver Damage in Rats
- Amelioration of D-Galactosamine-Induced Acute Liver Injury in Rats by Dietary Supplementation with Betaine Derived from Sugar Beet Molasses
- 97 A CASE OF A TRANSIENT FOCAL NEUROLOGIC DEFICIT ASSOCIATED WITH HYPOGLYCEMIA
- Effects of Dietary Supplementation with Betaine on a Nonalcoholic Steatohepatitis (NASH) Mouse Model
- Japanese Butterbur (Petasites japonicus) Leaves Increase Hepatic Oxidative Stress in Male Rats
- Raw Chinese Yam (Dioscorea opposita) Promotes Cecal Fermentation and Reduces Plasma Non-HDL Cholesterol Concentration in Rats
- Effects of Anthocyanin-rich Colored Potato Flakes on Lipid Oxidation, Instrumental Color Evaluation and Sensory Characteristics in Cooked Pork Sausages
- Dietary L-Cysteine Improves the Antioxidative Potential and Lipid Metabolism in Rats Fed a Normal Diet
- Effects of Dietary Supplementation with Betaine on a Nonalcoholic Steatohepatitis (NASH) Mouse Model
- Japanese Butterbur (Petasites japonicus) Leaves Increase Hepatic Oxidative Stress in Male Rats
- Resistant Starches of Beans Reduce the Serum Cholesterol Concentration in Rats
- Antioxidative Activity and Protective Effect against Ethanol-Induced Gastric Mucosal Damage of a Potato Protein Hydrolysate
- Two Phenolic Amides in the Seed Balls of Sugar Beet (Beta vulgaris L. var. saccharifera Alefeld)
- Influence of a Probiotic on Productivity, Meat Components, Lipid Metabolism, Caecal Flora and Metabolites, and Raising Environment in Broiler Production
- Effect of Potato Ethanol Residue on Rat Plasma Cholesterol Levels
- Comparison of the Effects of Longer Chain Inulins with Different Degrees of Polymerization on Colonic Fermentation in a Mixed Culture of Swine Fecal Bacteria