Comparative Hypocholesterolemic Effects of Five Animal Oils in Cholesterol-fed Rats
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概要
- 論文の詳細を見る
The hypocholesterolemic efficacy of various animal oils was compared in rats given a cholesterol-enriched diet. After acclimatization for one week, male F344 DuCrj rats (8 weeks of age) that had been fed with a conventional diet were assigned to diets containing 5% of oil from emu (Dromaius), Japanese Sika deer (Cervus nippon yesoensis, Heude), sardine, beef tallow, or lard with 0.5% cholesterol for 6 weeks. After this feeding period, the concentrations of serum total cholesterol and of very-low-density lipoprotein+intermediate-density lipoprotein+low-density lipoprotein-cholesterol in the sardine oil group were significantly lower than those in the other groups. The serum high-density lipoprotein-cholesterol concentration in the Japanese Sika deer oil group was significantly higher than that in the other groups. The atherosclerotic index and liver cholesterol concentration in the sardine oil and Japanese Sika deer oil groups were significantly lower than those in the other groups. The fecal cholesterol excretion by the Japanese Sika deer oil group was significantly higher than that of the other groups, except for the sardine oil group, and the fecal bile acid excretion by the sardine oil group was significantly higher than that of the other groups, except for the lard group. These results suggest that Japanese Sika deer oil reduced the atherosclerotic index and liver cholesterol concentration in the presence of excess cholesterol in the diet as well as sardine oil did by increasing the excretion of cholesterol from the intestines of rats.
- 社団法人日本農芸化学会の論文
- 1999-01-23
著者
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FUKUSHIMA Michihiro
Department of Agricultural and Life Science, Obihiro University of Agriculture and Veterinary Medici
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SEKIKAWA Mitsuo
Department of Food Science, Obihiro University of Agriculture and Veterinary Medicine
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Nakano M
Department Of Animal Science Obihiro University Of Agriculture And Veterinary Medicine
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Nakano Masuo
Department Of Bioresource Science Obihiro University Of Agriculture & Veterinary Medicine
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OHASHI Tetsu
Department of Bioresource Science, Obihiro University of Agriculture and Veterinary Medicine
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Nakano Masuo
Department Of Agro-environmental Science Obihiro University Of Agriculture And Veterinary Medicine
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Sekikawa Mitsuo
Dep. Of Animal Sci. Obihiro Univ. Of Agriculture And Veterinary Medicine
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Sekikawa Mitsuo
Department Of Agriculture And Life Science Obihiro University Of Agriculture And Veterinary Medicine
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Ohashi T
Department Of Bioresource Science Obihiro University Of Agriculture And Veterinary Medicine
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Sekikawa Mistuo
Department Of Animal And Food Hygiene Obihiro University Of Agriculture And Veterinary Medicine
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