Distribution of Body Weight, Blood Insulin and Lipid Levels in the SMXA Recombinant Inbred Strains and the QTL Analysis
スポンサーリンク
概要
- 論文の詳細を見る
In the SMXA recombinant inbred (RI) strains, we measured body weight, blood insulin and lipid (triglyceride, total cholesterol and phospholipid) levels in each strain. In the five traits, mean values of substrains varied remarkably and showed a continuous spectrum of distribution, suggesting control by multiple genes at distinct loci for each trait. We also screened for quantitative trait loci (QTLs) involved in the five traits. Suggestive QTLs for body weight (Chromosomes 1 and 6), insulin (Chromosomes 1, 3, 10 and 17), triglyceride (Chromosomes 4 and 11) and phospholipid (Chromosome 18) levels were detected. The SMXA RI strains are unique tools for analyzing genetic factors that influence body weight, blood insulin and lipids levels.
- 社団法人 日本実験動物学会の論文
著者
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NAMIKAWA Takao
Laboratory of Animal Genetics, Graduate School of Bioagricultural Sciences, Nagoya University
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ISHIKAWA Akira
Laboratory of Animal Genetics, Graduate School of Bioagricultural Sciences, Nagoya University
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TANAKA Shin
Animal Facility for Aging Research (AFAR), National Center for Geriatrics and Gerontology (NCGG)
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MORI Masayuki
Department of Aging Biology, Institute on Aging and Adaptation, Shinshu University Graduate School o
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OHNO Tamio
Institute for Laboratory Animal Research, Nagoya University School of Medicine
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TANAKA Shin
National Institute of Longevity Sciences, National Chubu Hospital
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NISHIMURA Masahiko
Institute for Laboratory Animal Research, Nagoya University School of Medicine
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HORIO Fumihiko
Division of Biomodeling, Graduate School of Bioagricultural Sciences, Nagoya University
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Ohno T
Division Of Experimental Animals Center For Promotion Of Medical Research And Education Graduate Sch
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Ohno Tamio
Division Of Experimental Animals Center For Promotion Of Medical Research And Education Graduate Sch
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Ohno Tamio
Institute For Laboratory Animal Research Graduate School Of Medicine Nagoya University
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Tanaka Shin
Animal Facility For Aging Research (afar) National Center For Geriatrics And Gerontology (ncgg)
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Mori M
Shinshu Univ. School Of Medicine Matsumoto Jpn
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Horio F
Nagoya Univ. Nagoya Jpn
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Horio Fumihiko
Department Of Applied Molecular Biosciences Graduate School Of Bioagricultural Sciences Nagoya Unive
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Namikawa T
Nagoya Univ. Nagoya Jpn
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Namikawa Takao
名古屋大学 生命農学研究科動物遺伝制御学
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Namikawa Takao
Laboratory Of Animal Genetics Department Of Applied Molecular Biosciences Graduate School Of Bioagri
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Namikawa Takao
Laboratry Of Animal Genetics Division Of Applied Genetics And Physiology
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ANUNCIADO Rea
College of Veterinary Medicine, University of the Philippines at Los Banos, College
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Nishimura M
Division Of Experimental Animals Center For Promotion Of Medical Research And Education Graduate Sch
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Nishimura Masahiko
Institute For Experimental Animals Hamamatsu University School Of Medicine
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Tanaka Shin
鹿児島大学 農学部獣医学科解剖学分野
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Nishimura Masahiko
Division Of Experimental Animals Center For Promotion Of Medical Research And Education Graduate Sch
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Anunciado Rea
Laboratory Of Animal Genetics Graduate School Of Bioagricultural Sciences Nagoya University.
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Mori Masayuki
Department Of Aging Angiology Research Cnter On Aging And Adaptation Shinshu University School Of Me
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Ishikawa A
Department Of Orthopaedic Surgery Yamagata University School Of Medicine
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Tanaka Shin
National Institute For Longevity Scienes
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Mori Masayuki
Department Of Aging Angiology Research Center On Aging And Adaptation Shinshu University School Of M
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Ishikawa Akira
Laboratory Of Animal Genetics Division Of Applied Genetics And Physiology Graduate School Of Bioagri
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