スンクスにおいて連鎖マッピングされた新規マイクロサテライトマーカー遺伝子座

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概要

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• Ten microsatellite DNA loci developed for the white-toothed shrew (Crocidura russula) were tested for PCR amplification and for utility in linkage studies in the house musk shrew, Suncus murinus. Four primer pairs successfully yielded PCR amplicons and showed polymorphism between two mutant strains, BAN-kc,oeb and WZ. Cloning and sequencing of the PCR amplicons of all the four loci confirmed the presence of microsatellite sequences. Alleles segregating in an F2 resource population constructed from the two strains ranged between two and five. Linkage analysis of the four loci together with 18 other polymorphic markers and three mutant loci resulted in five linkage groups containing three newly mapped microsatellite loci. This study reports the first microsatellite markers being registered in this species.

著者

• ISHIKAWA Akira

  Laboratory of Animal Genetics, Graduate School of Bioagricultural Sciences, Nagoya University

• ADJEI Samuel

  Laboratory of Animal Genetics, Department of Applied Molecular Biosciences, Graduate School of Bioag

• 石川 明

  Laboratory of Animal Genetics, School of Agricultural Sciences, Nagoya University

• Adjei Samuel

  名古屋大学 大学院生命農学研究科応用遺伝･生理学講座

• Adjei Samuel

  Laboratory Of Animal Genetics Department Of Applied Molecular Biosciences Graduate School Of Bioagri

• Ishikawa Akira

  Laboratory Of Animal Genetics Division Of Applied Genetics And Physiology Graduate School Of Bioagri

関連論文

• Quantitative Trait Loci for Glomerulosclerosis, Kidney Weight and Body Weight in the Focal Glomerulosclerosis Mouse Model
• Changes of Renal Lesion-Related Parameters in FGS/Nga and the Parental Mouse Strains, CBA/N and RFM/Nga
• マウス第12染色体上の成長QTL Pbwg12を導入したコンジェニック系統の樹立と特徴解析
• Open Eyelids at Birth, a New Mutation in the Musk Shrew, Suncus murinus
• Delayed Development of Reflexes and Hyperactive Locomotion in the Spontaneous Mutant "Waltzing" of the Musk Shrew, Suncus murinus
• スンクス, Suncus murinus におけるPCRとRFLPマーカーからなる遺伝的連鎖地図の作製
• Development and Characterization of CATS Markers for Genetic Linkage Mapping in the House Musk Shrew, Suncus murinus
• Mapping major quantitative trait loci for postnatal growth in an intersubspecific backcross between C57BL/6J and Philippine wild mice by using principal component analysis
• Quantitative Trait Locus Analysis of Serum Insulin, Triglyceride, Total Cholesterol and Phospholipid Levels in the (SM/J×A/J)F_2 Mice
• Quantitative Trait Loci for Body Weight in the Intercross between SM/J and A/J Mice
• Distribution of Body Weight, Blood Insulin and Lipid Levels in the SMXA Recombinant Inbred Strains and the QTL Analysis
• The Eye Lens Aplasia (elap) Maps to Mouse Chromosome 2
• スンクス(Suncus murinus)実験室系統における形態分化とmtDNA分化との関係
• スンクスにおいて連鎖マッピングされた新規マイクロサテライトマーカー遺伝子座
• A New Spontaneous Allele at the Pink-Eyed Dilution (p) Locus Discovered in Mus musculus castaneus
• マウス第12染色体上の成長QTL Pbwg12を導入したコンジェニック系統の樹立と特徴解析
• Hair Growth and Skin in the Kinky-Coat (kc) Musk, Shrew, Suncus murinus
• Arrest of Spermatogenesis at the Early Meiotic Stage in the Small Testis Mutant (Smt) Mice
• Characteristics of Reversion to Early Feathering Phenotype in the Late Feathering Line of Nagoya Breed Chickens

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