Effects of Histidine on Working Memory Deficits Induced by the 5-HT_<1A>-Receptor Agonist 8-OH-DPAT
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概要
- 論文の詳細を見る
We investigated the effects of histidine on spatial memory deficits induced by the 5-HT1A-receptor agonist, 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT). Working memory deficits were elicited by 8-OH-DPAT without affecting reference memory. Histidine improved the working memory deficit induced by 8-OH-DPAT at doses causing a significant increase in brain histamine content. This finding suggests that the histaminergic system regulates 8-OH-DPAT-induced working memory deficit.
- 社団法人 日本薬理学会の論文
- 2001-08-01
著者
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Kamei Chiaki
Department of Medicinal Pharmacology, Okayama University Graduate School of Medicine, Dentistry and
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Kamei C
岡山大学 医歯薬学総合研究科薬効解析学
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Kamei Chiaki
Dep. Of Medicinal Pharmacology Okayama Univ. Graduate School Of Medicine Dentistry And Pharmaceutica
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Kamei Chiaki
Departmment Of Pharmacology Faculty Of Pharmaceutical Siences Okayama University
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Kamei Chiaki
Department Of Pharmacology Faculty Of Pharmaceutical Sciences Okayama University Okayama
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SUGIMOTO Yukio
Departmment of Pharmacology, Faculty of Pharmaceutical Siences, Okayama University
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Sugimoto Yukio
Department Of Medicinal Pharmacology Okayama University Graduate School Of Medicine Dentistry And Ph
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NISHIGA Miyuki
Department of Pharmacology, Faculty of Pharmaceutical Sciences, Okayama University
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Nishiga Miyuki
Department Of Pharmacology Faculty Of Pharmaceutical Sciences Okayama University
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Kamei Chiaki
Department Of Medical Pharmacology Okayama University Graduate School Of Medicine Dentistry And Phar
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ISAYAMA Shinji
Department of Pharmacology, Faculty of Pharmaceutical Sciences, Okayama University
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Isayama Shinji
Department Of Pharmacology Faculty Of Pharmaceutical Sciences Okayama University
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