Geographical Variation in the Furanocoumarin and Polyacetylenic Compound Compositions of Wild Glehnia littoralis Plants

概要

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Glehnia littoralis, a medicinal plant of the family Umbelliferae growing wild on the sandy shores in Japan, was classified into N- and S-types on the basis of HPLC profiles of eight furanocoumarins and a polyacetylenic compound, panaxynol, in the underground part. The N-type plants, growing in the northern part of the country, contained more than 0.1% of furanocoumarins such as imperatorin, isoimperatorin, and 8-geranyloxypsoralen, whereas the S-type plants, distributing in the southern part, contained less than 0.1% of these components. The ratio of the panaxynol content to the total of eight furanocoumarin contents was 0-2 in the N-type plants and 10-100 in the S-type plants. The boundary regions of the distribution of the two types were found to be the Noto Peninsula on the Sea of Japan coast and the Sanriku Coast on the Pacific Ocean side.
日本生薬学会の論文
1997-02-20