Amino Acid Sequences and Ribosome-Inactivating Activities of Karasurin-B and Karasurin-C
スポンサーリンク
概要
- 論文の詳細を見る
Complete amino acid sequences of karasurin-B and karasurin-C purified from root tubers of Trichosanthes kirilowii MAXIM. var. japonica KITAMURA (Cucurbitaceae) were determined. Karasurin-B consists of 247 amino acid residues with a calculated molecular weight of 27214 Da and karasurin-C of 249 amino acid residues with a calculated molecular weight of 27401 Da. Their amino acid sequences are quite similar to that of karasurin-A, a major basic protein from the same root tubers, but the pI values are slightly different amoung them. All karasurins strongly inhibited in vitro translation in the rabbit reticulocyte system. The amino acid sequences of karasurins were compared with those of the ribosome-inactivating proteins (RIPs) from nine different species by UPGMA method, and the RIPs from Cucurbitaceae plants phylogenetically formed one cluster clearly distiguishable from those of other origin.
- 公益社団法人日本薬学会の論文
- 1996-11-15
著者
-
近藤 俊哉
Faculty Of Pharmaceutical Sciences Nagoya City University
-
Kondo T
Research Division The Green Cross Corporation
-
Ogihara Yukio
Laboratory Of Pharmacognosy Graduate School Of Pharmaceutical Sciences Nagoya City University
-
Ogihara Yukio
Faculty Of Pharmaceutical Sciences Nagoya City University
-
KONDO Toshiya
Faculty of Pharmaceutical Sciences, Kitasato University
-
Takeda Tadahiro
Kyoritsu College Of Pharmacy
-
Mizukami Hajime
Faculty Of Pharmaceutical Sciences Nagoya City University
-
Mizukami H
Dep. Of Pharmacognosy Graduate School Of Pharmaceutical Sciences Nagoya City Univ.
-
Takeda Tadahiro
Kyoritsu College Of Pharmac
-
Mizukami Hajime
Faculty Of Pharmaceutical Science Nagoya City University
関連論文
- Antidepressant-like effect of a Kampo (Japanese herbal) medicine, kososan, against the interferon-α-induced depressive-like model mice
- Cytotoxic Activity of Bryonolic Acid Isolated from Transformed Hairy Roots of Trichosanthes kirilowii var. japonica
- HPLC profiling of Phellinus linteus
- BRYONOLIC ACID PRODUCTION IN HAIRY ROOTS OF TRICHOSANTHES KIRILOWII MAX. VAR. JAPONICA KITAM. TRANSFORMED WITH AGROBACTERIUM RHIZOGENES AND ITS CYTOTOXIC ACTIVITY
- Anti-atherosclerotic action of Saikokaryukotsuboreito against apoE-deficient mice
- Phenylethanoid and Iridoid Glycosides from Veronica persica
- New Phenylethanoid Glycosides from Veronica pectinata var. glandulosa and Their Free Radical Scavenging Activities
- Anti-inflammatory and Cytotoxic Activities of Five Veronica Species
- Induction of Cytokines by a Phenylpropanoid Glycoside Acteoside
- Enhancement of Serum Nitric Oxide by Shichimotsu-koka-to (Kampo Medicine)
- Induction of Apoptotic Cell Death in HL-60 Cells by Acteoside, A Phenylpropanoid Glycoside
- A pea NTPase, PsAPY1, recognizes signal molecules from microorganisms
- Trypanocidal Effects of Curcumin in Vitro
- Formation of Reactive Oxygen Intermediates Might be Involved in the Trypanocidal Activity of Gallic Acid
- Catalase Contents in Cells Determine Sensitivity to the Apoptosis Inducer Gallic Acid
- Latifolosides K and L, Two New Triterpenoid Saponins from the Bark of Ilex latifolia
- Latifolosides I and J, Two New Triterpenoid Saponins from the Bark of Ilex latifolia
- Synthetic Studies on Glycosphingolipids from Protostomia Phyla : Synthesis of Amphoteric Glycolipid Analogues from the Porcine Nematode, Ascaris suum
- Ardisimamillosides G and H, Two New Triterpenoid Saponins from Ardisia mamillata
- Ardisimamillosides C-F, Four New Triterpenoid Saponins from Ardisia mamillata
- Effect of Matrix on Surface Pressure-Responsive Morphological Change of Ganglioside G_ (GM1), Related to the Individual Role of GM1 in Each Organ?
- Suppressive Effect of Kanzo-bushi-to, a Kampo Medicine, on Collagen-Induced Arthritis(Pharmacognosy)
- Evaluation of Kampo medicines used to treat rheumatoid arthritis in collagen-induced arthritic and pX transgenic mice
- Suppression of Macrophage Function by Substances with a Molecular Weight Lower than 3000 Da in B16 Melanoma-Conditioned Medium
- Suppressive Effect of Shichimotsu-koka-to (Kampo Medicine) on Pulmonary Metastasis of B16 Melanoma Cells
- Antimetastatic Activity of Acteoside, a Phenylethanoid Glycoside
- Inhibition of Cell Cycle Progression through Specific Phase by Pancratistatin Derivatives
- Cytotoxic activities of alkaloids from Zephyranthes carinata
- Different Generation of Inhibitors against Gallic Acid-Induced Apoptosis Produces Different Sensitivity to Gallic Acid
- Role of Reactive Oxygen Species in Gallic Acid-Induced Apoptosis
- Cell Death-Inducing Activity by Gallic Acid Derivatives
- Metabolic Fate of Gallic Acid Orally Administered to Rats
- Conformational Change of Ganglioside G_ with Surface Pressure, Related to Signal Transduction?
- Sulfated Triterpenoid Saponins from the Leaves of Bupleurum rotundifolium L.
- Lipid Peroxidation and the Antioxidant Effects of 3, 5, 7, 4'-Tetrahydroxy-2'-Methoxyflavone; Direct Observation by Atomic Force Microscopy
- イコサポリエン酸のミセル表面電位とミセル表面電位荷密度に及ぼす分子内二重結合の影響
- Induction of Defense Responses by Synthetic Glycopeptides that Have a Partial Structure of the Elicitor in the Spore Germination Fluid of Mycosphaerella Pinodes
- Synthetic Studies on Glycopeptides Concerned with Defense Response of Plants. I. Syntheses of Supprescins A and B
- EFFECTS OF SYNTHETIC GLYCOPEPTIDE-ELICITORS ON DEFENSE RESPONSES OF PEA PLANTS
- New Lignan Glycosides from Chinese Medicinal Plant, Sinopodophillum emodi
- A binding protein for fungal signal molecules in the cell wall of Pisum sativum
- Five New Triterpenoid Saponins from the Roots of Platycodon grandiflorum
- A New Flavonol Glycoside, Epimedin K, From Epimedium koreanum
- PC7 STUDIES ON ACTIVE PRINCIPLES OF SOME CHINESE TRADITIONAL MEDICINES
- Flavonoids from Sinopodophyllum emodi (Wall) Ying
- Two New Podophyllotoxin Glucosides from Sinopodophyllum emodi (WALL.) YING
- Novel Biphenyl Ether Lignans from the Rhizomes of Curcuma chuanyujin
- Inhibitory effect of oral intake of natural Phellinus linteus fruit body on growth and pulmonary metastasis of B16/BL6 melanoma
- P-174 Low molecular weight constituents in Phellinus linteus
- Iridoid Glucosides from Veronica hederifolia
- An Elicitor-Inducible NADP-Malic Enzyme in Lithospermum erythrorhizon Cultured Cells : cDNA Cloning and Characterization
- Comparative Study of the High Molecular Mass Fraction and Low Molecular Mass Fraction of Sho-saiko-to in a Murine Immunologically Induced Liver Injury Model
- Synthesis of 2-O-(4-Coumaroyl)-3-(4-hydroxyphenyl)lactic Acid, an Important Intermediate of Rosmarinic Acid Biosynthesis
- Cloning and Bacterial Expression of Karasurins, Ribosome-Inactivating Proteins (RIPs) from Trichosanthes Kirilowii var. Japonica
- Three New Glycosides from Sinopodophyllum emodi (WALL.) YING
- A New N-Methyltetrahydroprotoberberine Alkaloid from Tinospora hainanensis
- Purification and Characterization of UDP-Glucose : Curcumin Glucoside 1,6-Glucosyltransferase from Catharanthus roseus Cell Suspension Cultures
- DNA Authentication of Plantago Herb Based on Nucleotide Sequences of 18S-28S rRNA Internal Transcribed Spacer Region(Pharmacognosy)
- Sesquiterpenoid Derivatives from Ferula ferulioides. IV
- Sequiterpenoid Derivatives from Ferula ferulioides. III
- Sesquiterpenoid Derivatives from Ferula ferulioides. II.
- Fuhsioside, a New Phenylethanoid Glucoside from Veronica fuhsii
- Xanthones from Halenia corniculata
- Sesquiterpenoid Derivatives from Ferula ferulioides
- LONG-TERM ADMINISTRATION OF "SHO-SAIKO-TO" INCREASES CYTOCHROME P-450 mRNA LEVEL IN MOUSE LIVER
- A New Phenylethanoid Glycoside from Phlomis pungens WILLD. var. pungens
- Tetranortriterpenoids from Swietenia macrophylla
- Absolute Structure of Eremophilenolide from Soligago dahurica
- Effect of Karasurin-A on Nitric Oxide Production by Murine Macrophages and Mitogenic Response of Murine Splenocytes in Vitro
- Studies on Chemical Modification of Monensin IX. Synthesis of 26-Substituted Monensins and Their Na^+Ion Transport Activity
- STRUCTURAL TRANSFORMATION OF SAIKOSAPONINS BY GASTRIC JUICE AND INTESTINAL FLORA
- COMBINATION EFFECTS OF SHOSAIKOTO (CHINESE TRADITIONAL MEDICINE) AND PREDNISOLONE ON THE ANTI-INFLAMMATORY ACTION
- STUDIES OF THE COMBINED USE OF STEROID AND SHOSAIKOTO, ONE OF THE KAMPOHOZAI (CHINESE TRADITIONAL MEDICINE), ON PITUITARY ADRENOCORTICAL AXIS FUNCTION AND IMMUNE RESPONSES
- Minor Saponins from Tetrapanax papyriferum
- Triterpene Saponins from Tetrapanax papyriferum K. KOCH
- Synthesis of Phenoxyacetic Acid Derivatives as Highly Potent Antagonists of Gastrin/Cholecystokinin-B Receptors. III
- Synthesis of Phenoxyacetic Acid Derivatives as Highly Potent Antagonists of Gastrin/Cholecystokinin-B Receptors. II
- Synthesis of Phenoxyacetic Acid Derivatives as Highly Potent Antagonists of Gastrin/Cholecystokinin-B Receptors
- COMPARATIVE STUDIES OF THE STEREOISOMERS OF GLYCYRRHETINIC ACID ON ANTI-INFLAMMATORY ACTIVITIES
- Novel Histamine H_3 Receptor Antagonists : Synthesis and Evaluation of Formamidine and S-Methylisothiourea Derivatives
- CLONING AND BACTERIAL EXPRESSION OF A GENE ENCODING RIBOSOME-INACTIVATING PROTEINS, KARASURIN-A AND KARASURIN-C, FROM TRICHOSANTHES KIRILOWII VAR. JAPONICA
- Studies on the Constituents of Calliandra anomala (KUNTH) MACBR. IV. Structure Analysis by HPLC Retention Time and FAB-MS Spectrum
- Basic Proteins Produced by Hairy Root Cultures of Trichosanthes Kirilowii var. japonica
- Studies on the Constituents of Calliandra anomala (KUNTH) MACBR. III. Structure Elucidation of Six Acylated Triterpenoidal Saponins
- Activation of Macrophages by Crude Polysaccharide Fractions Obtained from Shoots of Glycyrrhiza blabra and Hairy Roots of Glycyrrhiza uralensis in Vitro
- The Effects of Crude Polysaccharide Fractions of 4 Kinds of Kampo-hozai Administered Orally on Nitric Oxide Production by Murine Peritoneal Macrophages
- STUDIES ON THE COMBINATION OF GLYCYRRHIZAE RADIX IN SHAKUYAKUKANZO-TO
- STRUCTURE-ACTIVITY STUDIES OF SOME OLEANANE TRITERPENOID GLYCOSIDES AND THEIR RELATED COMPOUNDS FROM THE LEAVES OF TETRAPANAX PAPYRIFERUM ON ANTI-INFLAMMATORY ACTIVITIES
- ANTI-INFLAMMATORY TESTING METHODS : COMPARATIVE EVALUATION OF MICE AND RATS
- Amino Acid Sequences and Ribosome-Inactivating Activities of Karasurin-B and Karasurin-C
- BLOCKADE BY ANTI-GLUCOCORTICOIDS, ACTINOMYCIN D AND CYCLOHEXIMIDE OF THE ANTI-INFLAMMATORY ACTION OF SOME KAMPOHOZAI (CHINESE TRADITIONAL MEDICINES) AGAINST SEROTONIN
- Absolute Structure of (S)-Trans-N-Methyltetrahydroprotoberberine Alkaloid, β-Cyclanoline
- Positive and Negative Ion Mass Spectra of Flavonoid Glycosides by Fast Atom Bombardment
- Flavonoids from Sinopodophyllum emodi (Wall) Ying(Natural Medicine Note)
- Triterpenoids from stem bark of Ilex latifolia(Natural Medicine Note)
- Xanthones from Gentiana acuta(Natural Medicine Note)
- Flavonoids from Hedysarum taipeicum(Natural Medicine Note)
- Cytotoxic activities of alkaloids from Zephyranthes carinata
- Chemical Constituents of Pimpinella magna(Natural Medicine Note)
- Studies on the Glycosides from Buddleja americana L.