Antimetastatic Activity of Acteoside, a Phenylethanoid Glycoside
スポンサーリンク
概要
- 論文の詳細を見る
We examined the antimetastatic effect of acteoside, a phenylethanoid glycoside widely distributed in the plant kingdom, on lung metastasis using a mouse model injected with B16 melanoma cells intravenously. Male C57BL/6 mice were injected intravenously with 2×10^5 of B16 melanoma cells, while acteoside at a dose of 50mg/kg was administered intraperitoneally every other day from 13 d before B16 melanoma cell injection until all mice had succumbed to the metastatic tumor burden in the lung. Administration of acteoside prolonged survival time significantly and the average survival time was 63.3±3.4d compared with 52.1±2.5d in control mice. This result suggests that acteoside showed suppressive effect on lung metastasis of B16 melanoma cells.
- 公益社団法人日本薬学会の論文
- 2002-05-01
著者
-
SARACOGLU Iclal
Department of Pharmacognosy, Faculty of Pharmacy, Hacettepe University
-
Inoue Makoto
名古屋市立大学 薬研究生薬学
-
Inoue M
Lab. Of Medicinal Resources School Of Pharmacy Aichi Gakuin Univ.
-
Saracoglu Iclal
Department Of Pharmacognosy Faculty Of Pharmacy Hacettepe University
-
Saracoglu Iclal
トルコ
-
OGIHARA Yukio
Nihon Pharmaceutical University
-
Ogihara Y
Nihon Pharmaceutical University
-
Ogihara Yukio
Laboratory Of Pharmacognosy Graduate School Of Pharmaceutical Sciences Nagoya City University
-
Ogihara Yukio
Faculty Of Pharmacy Meijo Universitv
-
Ogihara Yukio
Graduate School Of Pharmaceutical Sciences Nagoya City University
-
Inoue M
Laboratory Of Pharmacognosy Graduate School Of Pharmaceutical Sciences Nagoya City University
-
INOUE Makoto
Laboratory of Pharmacognosy, Graduate School of Pharmaceutical Sciences, Nagoya City University
-
Ohno T
Biomedical Research Laboratories
-
Ohno T
Department Of Chemical Analysis Pharmaceutical Research Laboratories Dainippon Pharmaceutical Co. Lt
-
大野 智子
Department Of Chemical Analysis Pharmaceutical Research Laboratories Dainippon Pharmaceutical Co. Lt
-
Ohno T
Laboratory Of Medicinal Resources School Of Pharmacy Aichi Gakuin University
-
Ohno Takamasa
Laboratory of Pharmacognosy, Graduate School of Pharmaceutical Sciences, Nagoya City University
-
Ohno Tetsuji
Biomedical Research Laboratories
-
Ohno Takamasa
Department Of Cardiology Regeneration Medicine And Bioethics Gifu University Graduate School Of Medi
-
Saracoglu I
Department Of Pharmacognosy Faculty Of Pharmacy Hacettepe University
-
Ohno Takamasa
Laboratory Of Medicinal Resources School Of Pharmacy Aichi Gakuin University
-
Inoue Makoto
Laboratory Of Metabolic Biochemistry Faculty Of Agriculture Tottori University
-
Inoue Makoto
Laboratory of Medicinal Resources, School of Pharmacy, Aichi Gakuin University
関連論文
- G-062(30) 関節リウマチに対する漢方方剤の評価 : 関節破壊に対する甘草附子湯の効果
- A-010(31) 動脈硬化発症モデルマウス apoE KO マウスにおける柴胡加竜骨牡蛎湯の効果
- 漢方の科学的評価 : 第29報 慢性関節リウマチに有効な漢方方剤の解析 : CIA マウスと pX トランスジェニックマウスに及ぼす影響 : 炎症 (1)
- 28D-04 漢方の科学的評価(第 19 報) : 黄耆桂枝五物湯加紅参の脂質代謝酵素に及ぼす影響
- Studies on Constituents with Cytotoxic and Cytostatic Activity of Two Turkish Medicinal Plants Phlomis armeniaca and Scutellaria salviifolia
- HPLC profiling of Phellinus linteus
- Anti-atherosclerotic action of Saikokaryukotsuboreito against apoE-deficient mice
- Phenylethanoid and Iridoid Glycosides from Veronica persica
- New Phenylethanoid Glycosides from Veronica pectinata var. glandulosa and Their Free Radical Scavenging Activities
- Anti-inflammatory and Cytotoxic Activities of Five Veronica Species
- Induction of Cytokines by a Phenylpropanoid Glycoside Acteoside
- Enhancement of Serum Nitric Oxide by Shichimotsu-koka-to (Kampo Medicine)
- Induction of Apoptotic Cell Death in HL-60 Cells by Acteoside, A Phenylpropanoid Glycoside
- Leishmanicidal Effect of Curcumin in Vitro
- Trypanocidal Effects of Curcumin in Vitro
- Formation of Reactive Oxygen Intermediates Might be Involved in the Trypanocidal Activity of Gallic Acid
- Catalase Contents in Cells Determine Sensitivity to the Apoptosis Inducer Gallic Acid
- Ca^-Dependent Caspase Activation by Gallic Acid Derivatives
- Latifolosides K and L, Two New Triterpenoid Saponins from the Bark of Ilex latifolia
- Latifolosides I and J, Two New Triterpenoid Saponins from the Bark of Ilex latifolia
- Sesquiterpene Lactone Suppresses Vascular Smooth Muscle Cell Proliferation and Migration via Inhibition of Cell Cycle Progression(Pharmacognosy)
- Ardisimamillosides C-F, Four New Triterpenoid Saponins from Ardisia mamillata
- Repression of Acyl-CoA : Cholesterol Acyltransferase by a Traditional Herbal Medicine (Kampo Meidcine), Ogi-Keishi-Gomotsu-To-Ka-Kojin
- Antihyperlipidemic Action of Ogi-Keishi-Gomotsu-To-Ka-Kojin against Cyclophosphamide-Induced Hyperlipidemia in Rabbits
- Antihypercholesterolemic Action of a Traditional Chinese Medicine (Kampo Medicine), Ogi-Keichi-Gomotsu-To-Ka-Kojin
- Suppressive Effect of Kanzo-bushi-to, a Kampo Medicine, on Collagen-Induced Arthritis(Pharmacognosy)
- Suppressive Effect of Dai-bofu-to on Collagen-Induced Arthritis(Pharmacognosy)
- Evaluation of Kampo medicines used to treat rheumatoid arthritis in collagen-induced arthritic and pX transgenic mice
- Suppression of Macrophage Function by Substances with a Molecular Weight Lower than 3000 Da in B16 Melanoma-Conditioned Medium
- Suppressive Effect of Shichimotsu-koka-to (Kampo Medicine) on Pulmonary Metastasis of B16 Melanoma Cells
- Antimetastatic Activity of Acteoside, a Phenylethanoid Glycoside
- Inhibition of Cell Cycle Progression through Specific Phase by Pancratistatin Derivatives
- Cytotoxic activities of alkaloids from Zephyranthes carinata
- Different Generation of Inhibitors against Gallic Acid-Induced Apoptosis Produces Different Sensitivity to Gallic Acid
- Role of Reactive Oxygen Species in Gallic Acid-Induced Apoptosis
- Cell Death-Inducing Activity by Gallic Acid Derivatives
- Metabolic Fate of Gallic Acid Orally Administered to Rats
- Sulfated Triterpenoid Saponins from the Leaves of Bupleurum rotundifolium L.
- Synthetic Studies on Glycopeptides Concerned with Defense Response of Plants. I. Syntheses of Supprescins A and B
- New Lignan Glycosides from Chinese Medicinal Plant, Sinopodophillum emodi
- A New Flavonol Glycoside, Epimedin K, From Epimedium koreanum
- PC7 STUDIES ON ACTIVE PRINCIPLES OF SOME CHINESE TRADITIONAL MEDICINES
- Flavonoids from Sinopodophyllum emodi (Wall) Ying
- Two New Podophyllotoxin Glucosides from Sinopodophyllum emodi (WALL.) YING
- Novel Biphenyl Ether Lignans from the Rhizomes of Curcuma chuanyujin
- Secondary Metabolism of Dinitrobenzyl Glucuronide Related to Production of Genotoxic Compounds of Dinitrotoluene in Male Wistar Rat
- Synthesis of Pyridinium Dinitrobenzyl Sulfates and Potassium (Dinitrobenzyl β-D-Glucopyranosid)Uronates
- Inhibitory effect of oral intake of natural Phellinus linteus fruit body on growth and pulmonary metastasis of B16/BL6 melanoma
- P-174 Low molecular weight constituents in Phellinus linteus
- Iridoid Glucosides from Veronica hederifolia
- An Elicitor-Inducible NADP-Malic Enzyme in Lithospermum erythrorhizon Cultured Cells : cDNA Cloning and Characterization
- New Sesquiterpenes from Ferulaferulaeoides (STEUD.) KOROVIN. VI. Isolation and Identification of Three New Dihydrofuro[2,3-b]chromones
- Comparative Study of the High Molecular Mass Fraction and Low Molecular Mass Fraction of Sho-saiko-to in a Murine Immunologically Induced Liver Injury Model
- Synthesis of 2-O-(4-Coumaroyl)-3-(4-hydroxyphenyl)lactic Acid, an Important Intermediate of Rosmarinic Acid Biosynthesis
- Cloning and Bacterial Expression of Karasurins, Ribosome-Inactivating Proteins (RIPs) from Trichosanthes Kirilowii var. Japonica
- Three New Glycosides from Sinopodophyllum emodi (WALL.) YING
- A New N-Methyltetrahydroprotoberberine Alkaloid from Tinospora hainanensis
- Sesquiterpenoid Derivatives from Ferula ferulioides. V
- Sesquiterpenoid Derivatives from Ferula ferulioides. IV
- Sequiterpenoid Derivatives from Ferula ferulioides. III
- Sesquiterpenoid Derivatives from Ferula ferulioides. II.
- Fuhsioside, a New Phenylethanoid Glucoside from Veronica fuhsii
- Xanthones from Halenia corniculata
- Sesquiterpenoid Derivatives from Ferula ferulioides
- LONG-TERM ADMINISTRATION OF "SHO-SAIKO-TO" INCREASES CYTOCHROME P-450 mRNA LEVEL IN MOUSE LIVER
- A New Phenylethanoid Glycoside from Phlomis pungens WILLD. var. pungens
- Tetranortriterpenoids from Swietenia macrophylla
- Absolute Structure of Eremophilenolide from Soligago dahurica
- Effect of Karasurin-A on Nitric Oxide Production by Murine Macrophages and Mitogenic Response of Murine Splenocytes in Vitro
- Peroxisome Proliferator-Activated Receptor γ Ligands Isolated from Adlay Seed(Coix lacryma-jobi L. var. ma-yuen STAPF)(Pharmacognosy)
- Phellifuropyranone A : A New Furopyranone Compound Isolated from Fruit Bodies of Wild Phellinus linteus
- ILVII-3 Kampo Medicines (Herbal Prescriptions in Japanese Traditional Medicine) as Molecular Library for Drug Development(Chemistry and Biochemistry Related to Biodiversity)
- Studies on Chemical Modification of Monensin IX. Synthesis of 26-Substituted Monensins and Their Na^+Ion Transport Activity
- STRUCTURAL TRANSFORMATION OF SAIKOSAPONINS BY GASTRIC JUICE AND INTESTINAL FLORA
- COMBINATION EFFECTS OF SHOSAIKOTO (CHINESE TRADITIONAL MEDICINE) AND PREDNISOLONE ON THE ANTI-INFLAMMATORY ACTION
- STUDIES OF THE COMBINED USE OF STEROID AND SHOSAIKOTO, ONE OF THE KAMPOHOZAI (CHINESE TRADITIONAL MEDICINE), ON PITUITARY ADRENOCORTICAL AXIS FUNCTION AND IMMUNE RESPONSES
- Minor Saponins from Tetrapanax papyriferum
- Triterpene Saponins from Tetrapanax papyriferum K. KOCH
- Synthesis of Phenoxyacetic Acid Derivatives as Highly Potent Antagonists of Gastrin/Cholecystokinin-B Receptors. III
- Synthesis of Phenoxyacetic Acid Derivatives as Highly Potent Antagonists of Gastrin/Cholecystokinin-B Receptors. II
- Synthesis of Phenoxyacetic Acid Derivatives as Highly Potent Antagonists of Gastrin/Cholecystokinin-B Receptors
- Restorative Effect of Shosaikoto (Kampo Medicine) on Diminution of Nitric Oxide Synthesis in Murine Peritoneal Macrophages induced by Hyperocholesterolemia
- Anti-hyperlipidemic and Anti-atherosclerotic Actions of Shosaikoto (Kampo Medicine)
- SHOSAIKOTO (KAMPO MEDICINE) PROTECTS MACROPHAGE FUNCTION FROM SUPPRESSION BY HYPERCHOLESTEROLEMIA
- COMPARATIVE STUDIES OF THE STEREOISOMERS OF GLYCYRRHETINIC ACID ON ANTI-INFLAMMATORY ACTIVITIES
- CLONING AND BACTERIAL EXPRESSION OF A GENE ENCODING RIBOSOME-INACTIVATING PROTEINS, KARASURIN-A AND KARASURIN-C, FROM TRICHOSANTHES KIRILOWII VAR. JAPONICA
- Studies on the Constituents of Calliandra anomala (KUNTH) MACBR. IV. Structure Analysis by HPLC Retention Time and FAB-MS Spectrum
- Basic Proteins Produced by Hairy Root Cultures of Trichosanthes Kirilowii var. japonica
- Studies on the Constituents of Calliandra anomala (KUNTH) MACBR. III. Structure Elucidation of Six Acylated Triterpenoidal Saponins
- Activation of Macrophages by Crude Polysaccharide Fractions Obtained from Shoots of Glycyrrhiza blabra and Hairy Roots of Glycyrrhiza uralensis in Vitro
- The Effects of Crude Polysaccharide Fractions of 4 Kinds of Kampo-hozai Administered Orally on Nitric Oxide Production by Murine Peritoneal Macrophages
- Amino Acid Sequences and Ribosome-Inactivating Activities of Karasurin-B and Karasurin-C
- Absolute Structure of (S)-Trans-N-Methyltetrahydroprotoberberine Alkaloid, β-Cyclanoline
- Flavonoids from Sinopodophyllum emodi (Wall) Ying(Natural Medicine Note)
- Triterpenoids from stem bark of Ilex latifolia(Natural Medicine Note)
- Xanthones from Gentiana acuta(Natural Medicine Note)
- Flavonoids from Hedysarum taipeicum(Natural Medicine Note)
- Cytotoxic activities of alkaloids from Zephyranthes carinata
- Studies on the Glycosides from Buddleja americana L.
- Synthesis of Methyl 2,3-, 2,4- and 3,4-Di-O-Methyl-α-D-Fucopyranosides