Activation of Macrophages by Crude Polysaccharide Fractions Obtained from Shoots of Glycyrrhiza blabra and Hairy Roots of Glycyrrhiza uralensis in Vitro
スポンサーリンク
概要
- 論文の詳細を見る
Many plant polysaccharide fractions have been reported as immunomodulatory agents. However, sometimes the possibility of contamination with bacterial lipopolysaccharide (LPS), a potent B cell mitogen and immune modulator, is discussed. In the present paper, we investigated the effects of crude polysaccharide fractions obtained from the shoot and hairy root of Glycyrrhizae sp. on murine peritoneal macrophage function, in order to clarify whether plants grown under aseptic conditions produce immunomodulatory polysaccharides. All crude polysaccharide fractions induced nitric oxide production by murine peritoneal macrophages in vitro. Chemical analysis revealed that LPS-like molecules were not present in all preparations. These results suggested that shoot and hairy root biosynthesized polysaccharides that could stimulate macrophages de novo.
- 公益社団法人日本薬学会の論文
- 1998-10-15
著者
-
Ogihara Yukio
Laboratory Of Pharmacognosy Graduate School Of Pharmaceutical Sciences Nagoya City University
-
Ogihara Yukio
Department Of Pharmacognosy And Plant Chemistry Faculty Of Pharmaceutical Sciences Nagoya City Unive
-
Ogihara Yukio
Graduate School Of Pharmaceutical Sciences Nagoya City University
-
NOSE Mitsuhiko
Laboratory of Pharmacognosy, Graduate School of Pharmaceutical Sciences, Nagoya City University
-
NOSE Mitsuhiko
Department of Pharmacognosy and Plant Chemistry, Faculty of Pharmaceutical Sciences, Nagoya City Uni
-
Shimomura Koichiro
Tsukuba Medicinal Plant Research Station National Institute Of Health Sciences
-
TERAWAKI Kiyoshi
Laboratory of Pharmacognosy, Graduate School of Pharmaceutical Sciences, Nagoya City University
-
OGURI Kanayo
Laboratory of Pharmacognosy, Graduate School of Pharmaceutical Sciences, Nagoya City University
-
Nose M
Laboratory Of Pharmacognosy Graduate School Of Pharmaceutical Sciences Nagoya City University
-
Yoshimatsu Kayo
Tsukuba Division Research Center For Medicinal Plant Resources National Instituite Of Biomedical Inn
-
Oguri K
Laboratory Of Pharmacognosy Graduate School Of Pharmaceutical Sciences Nagoya City University
-
TERAWAKI kiyoshi
Department of Pharmacognosy and Plant Chemistry, Faculty of Pharmaceutical Sciences, Nagoya City Uni
-
OGURI Kanayo
Department of Pharmacognosy and Plant Chemistry, Faculty of Pharmaceutical Sciences, Nagoya City Uni
-
Terawaki Kiyoshi
Laboratory Of Pharmacognosy Graduate School Of Pharmaceutical Sciences Nagoya City University
-
Shimomura Koichiro
Tsukuba Medicinal Plant Research Station National Institute Of Health Science
-
Yoshimatsu Kayo
Tsukuba Div. Res. Center For Medicinal Plant Resources National Inst. Of Biomedical Innovation
関連論文
- G-062(30) 関節リウマチに対する漢方方剤の評価 : 関節破壊に対する甘草附子湯の効果
- A-010(31) 動脈硬化発症モデルマウス apoE KO マウスにおける柴胡加竜骨牡蛎湯の効果
- 漢方の科学的評価 : 第29報 慢性関節リウマチに有効な漢方方剤の解析 : CIA マウスと pX トランスジェニックマウスに及ぼす影響 : 炎症 (1)
- 28D-04 漢方の科学的評価(第 19 報) : 黄耆桂枝五物湯加紅参の脂質代謝酵素に及ぼす影響
- 28B-01 漢方の科学的評価(第 20 報) : 慢性関節リウマチに使用される漢方方剤のコラーゲン誘発関節炎モデルによる評価
- HPLC profiling of Phellinus linteus
- 36 モンゴル産薬用植物Ferula ferulioidesに含まれる新規セスキテルペン誘導体の構造(口頭発表の部)
- Anti-atherosclerotic action of Saikokaryukotsuboreito against apoE-deficient mice
- Phenylethanoid and Iridoid Glycosides from Veronica persica
- New Phenylethanoid Glycosides from Veronica pectinata var. glandulosa and Their Free Radical Scavenging Activities
- Anti-inflammatory and Cytotoxic Activities of Five Veronica Species
- Induction of Cytokines by a Phenylpropanoid Glycoside Acteoside
- Enhancement of Serum Nitric Oxide by Shichimotsu-koka-to (Kampo Medicine)
- Induction of Apoptotic Cell Death in HL-60 Cells by Acteoside, A Phenylpropanoid Glycoside
- Leishmanicidal Effect of Curcumin in Vitro
- Trypanocidal Effects of Curcumin in Vitro
- Formation of Reactive Oxygen Intermediates Might be Involved in the Trypanocidal Activity of Gallic Acid
- Novel Functions of Herbal Medicines in Dendritic Cells : Role of Amomi Semen in Tumor Immunity
- Catalase Contents in Cells Determine Sensitivity to the Apoptosis Inducer Gallic Acid
- Ca^-Dependent Caspase Activation by Gallic Acid Derivatives
- Latifolosides K and L, Two New Triterpenoid Saponins from the Bark of Ilex latifolia
- Latifolosides I and J, Two New Triterpenoid Saponins from the Bark of Ilex latifolia
- Ardisimamillosides C-F, Four New Triterpenoid Saponins from Ardisia mamillata
- Repression of Acyl-CoA : Cholesterol Acyltransferase by a Traditional Herbal Medicine (Kampo Meidcine), Ogi-Keishi-Gomotsu-To-Ka-Kojin
- Antihyperlipidemic Action of Ogi-Keishi-Gomotsu-To-Ka-Kojin against Cyclophosphamide-Induced Hyperlipidemia in Rabbits
- Antihypercholesterolemic Action of a Traditional Chinese Medicine (Kampo Medicine), Ogi-Keichi-Gomotsu-To-Ka-Kojin
- Suppressive Effect of Kanzo-bushi-to, a Kampo Medicine, on Collagen-Induced Arthritis(Pharmacognosy)
- Evaluation of Kampo medicines used to treat rheumatoid arthritis in collagen-induced arthritic and pX transgenic mice
- Suppression of Macrophage Function by Substances with a Molecular Weight Lower than 3000 Da in B16 Melanoma-Conditioned Medium
- Suppressive Effect of Shichimotsu-koka-to (Kampo Medicine) on Pulmonary Metastasis of B16 Melanoma Cells
- Antimetastatic Activity of Acteoside, a Phenylethanoid Glycoside
- Inhibition of Cell Cycle Progression through Specific Phase by Pancratistatin Derivatives
- Cytotoxic activities of alkaloids from Zephyranthes carinata
- Different Generation of Inhibitors against Gallic Acid-Induced Apoptosis Produces Different Sensitivity to Gallic Acid
- Role of Reactive Oxygen Species in Gallic Acid-Induced Apoptosis
- Cell Death-Inducing Activity by Gallic Acid Derivatives
- Metabolic Fate of Gallic Acid Orally Administered to Rats
- Sulfated Triterpenoid Saponins from the Leaves of Bupleurum rotundifolium L.
- New Lignan Glycosides from Chinese Medicinal Plant, Sinopodophillum emodi
- A New Flavonol Glycoside, Epimedin K, From Epimedium koreanum
- PC7 STUDIES ON ACTIVE PRINCIPLES OF SOME CHINESE TRADITIONAL MEDICINES
- Flavonoids from Sinopodophyllum emodi (Wall) Ying
- Two New Podophyllotoxin Glucosides from Sinopodophyllum emodi (WALL.) YING
- Novel Biphenyl Ether Lignans from the Rhizomes of Curcuma chuanyujin
- Inhibitory effect of oral intake of natural Phellinus linteus fruit body on growth and pulmonary metastasis of B16/BL6 melanoma
- P-174 Low molecular weight constituents in Phellinus linteus
- Iridoid Glucosides from Veronica hederifolia
- An Elicitor-Inducible NADP-Malic Enzyme in Lithospermum erythrorhizon Cultured Cells : cDNA Cloning and Characterization
- New Sesquiterpenes from Ferulaferulaeoides (STEUD.) KOROVIN. VI. Isolation and Identification of Three New Dihydrofuro[2,3-b]chromones
- Comparative Study of the High Molecular Mass Fraction and Low Molecular Mass Fraction of Sho-saiko-to in a Murine Immunologically Induced Liver Injury Model
- Synthesis of 2-O-(4-Coumaroyl)-3-(4-hydroxyphenyl)lactic Acid, an Important Intermediate of Rosmarinic Acid Biosynthesis
- Cloning and Bacterial Expression of Karasurins, Ribosome-Inactivating Proteins (RIPs) from Trichosanthes Kirilowii var. Japonica
- Three New Glycosides from Sinopodophyllum emodi (WALL.) YING
- A New N-Methyltetrahydroprotoberberine Alkaloid from Tinospora hainanensis
- Effects of Kampo-hozais on the Induction of Oral Tolerance to Ovalbumin in Mice
- Comparison of Immunopharmacological Actions of 8 Kinds of Kampo-Hozais Clinically Used in Atopic Dermatitis on Delayed-Type Hypersensitivity in Mice
- Effect of Hachimi-jio-gan on Immunoglobulin A Producing Cells in Peyer's Patch by Oral Administration
- Sesquiterpenoid Derivatives from Ferula ferulioides. V
- Sesquiterpenoid Derivatives from Ferula ferulioides. IV
- Sequiterpenoid Derivatives from Ferula ferulioides. III
- Sesquiterpenoid Derivatives from Ferula ferulioides. II.
- Fuhsioside, a New Phenylethanoid Glucoside from Veronica fuhsii
- Xanthones from Halenia corniculata
- Sesquiterpenoid Derivatives from Ferula ferulioides
- LONG-TERM ADMINISTRATION OF "SHO-SAIKO-TO" INCREASES CYTOCHROME P-450 mRNA LEVEL IN MOUSE LIVER
- A New Phenylethanoid Glycoside from Phlomis pungens WILLD. var. pungens
- Tetranortriterpenoids from Swietenia macrophylla
- Absolute Structure of Eremophilenolide from Soligago dahurica
- Effect of Karasurin-A on Nitric Oxide Production by Murine Macrophages and Mitogenic Response of Murine Splenocytes in Vitro
- Studies on Chemical Modification of Monensin IX. Synthesis of 26-Substituted Monensins and Their Na^+Ion Transport Activity
- Choleretic Actions of Iridoid Compounds
- STRUCTURAL TRANSFORMATION OF SAIKOSAPONINS BY GASTRIC JUICE AND INTESTINAL FLORA
- COMBINATION EFFECTS OF SHOSAIKOTO (CHINESE TRADITIONAL MEDICINE) AND PREDNISOLONE ON THE ANTI-INFLAMMATORY ACTION
- The Effect of Keishi-bushi-to on Collagen-Induced Arthritis
- Effect of Shosaikoto (Kampo Medicine) on the Adherence of Monocytes in Hypercholesterolemic Rabbit
- Minor Saponins from Tetrapanax papyriferum
- Triterpene Saponins from Tetrapanax papyriferum K. KOCH
- Synthesis of Phenoxyacetic Acid Derivatives as Highly Potent Antagonists of Gastrin/Cholecystokinin-B Receptors. III
- Synthesis of Phenoxyacetic Acid Derivatives as Highly Potent Antagonists of Gastrin/Cholecystokinin-B Receptors. II
- Synthesis of Phenoxyacetic Acid Derivatives as Highly Potent Antagonists of Gastrin/Cholecystokinin-B Receptors
- Restorative Effect of Shosaikoto (Kampo Medicine) on Diminution of Nitric Oxide Synthesis in Murine Peritoneal Macrophages induced by Hyperocholesterolemia
- Anti-hyperlipidemic and Anti-atherosclerotic Actions of Shosaikoto (Kampo Medicine)
- SHOSAIKOTO (KAMPO MEDICINE) PROTECTS MACROPHAGE FUNCTION FROM SUPPRESSION BY HYPERCHOLESTEROLEMIA
- CLONING AND BACTERIAL EXPRESSION OF A GENE ENCODING RIBOSOME-INACTIVATING PROTEINS, KARASURIN-A AND KARASURIN-C, FROM TRICHOSANTHES KIRILOWII VAR. JAPONICA
- Studies on the Constituents of Calliandra anomala (KUNTH) MACBR. IV. Structure Analysis by HPLC Retention Time and FAB-MS Spectrum
- Basic Proteins Produced by Hairy Root Cultures of Trichosanthes Kirilowii var. japonica
- Studies on the Constituents of Calliandra anomala (KUNTH) MACBR. III. Structure Elucidation of Six Acylated Triterpenoidal Saponins
- Activation of Macrophages by Crude Polysaccharide Fractions Obtained from Shoots of Glycyrrhiza blabra and Hairy Roots of Glycyrrhiza uralensis in Vitro
- The Effects of Crude Polysaccharide Fractions of 4 Kinds of Kampo-hozai Administered Orally on Nitric Oxide Production by Murine Peritoneal Macrophages
- STUDIES ON THE COMBINATION OF GLYCYRRHIZAE RADIX IN SHAKUYAKUKANZO-TO
- STRUCTURE-ACTIVITY STUDIES OF SOME OLEANANE TRITERPENOID GLYCOSIDES AND THEIR RELATED COMPOUNDS FROM THE LEAVES OF TETRAPANAX PAPYRIFERUM ON ANTI-INFLAMMATORY ACTIVITIES
- ANTI-INFLAMMATORY TESTING METHODS : COMPARATIVE EVALUATION OF MICE AND RATS
- Amino Acid Sequences and Ribosome-Inactivating Activities of Karasurin-B and Karasurin-C
- Absolute Structure of (S)-Trans-N-Methyltetrahydroprotoberberine Alkaloid, β-Cyclanoline
- Flavonoids from Sinopodophyllum emodi (Wall) Ying(Natural Medicine Note)
- Triterpenoids from stem bark of Ilex latifolia(Natural Medicine Note)
- Xanthones from Gentiana acuta(Natural Medicine Note)
- Flavonoids from Hedysarum taipeicum(Natural Medicine Note)
- Cytotoxic activities of alkaloids from Zephyranthes carinata
- Studies on the Glycosides from Buddleja americana L.