Conformational Change of Ganglioside G_<M1> with Surface Pressure, Related to Signal Transduction?

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概要

• 論文の詳細を見る

• Gangliosides participate in cellular interactions and signal transductions. An initial step in those processes is glycolipid interaction. We observed the conformational change of ganglioside GM1 (GM1) at the membrane surface by means of atomic force microscopy (AFM), and revealed the following changes of GM1 with increasing surface pressure : a uniform pattern at 29 mN/m, a swelling pattern at 33 mN/m, and a return to a uniform pattern at 40 mN/m. This behavior is thought to be related to specific cell recognition or signal transduction, and may prove useful for elucidating the functions of glycolipid microdomains in biological membranes.

• 日本油化学会の論文
• 2001-11-01

著者

• Abe Masahiko

  Fac. Of Sci. And Technol. Tokyo Univ. Of Sci.

• Abe Masahiko

  東京理科大学 理工学部

• TAKEDA Tadahiro

  Kyoritsu University of Pharmacy

• Imura Tomohiro

  Research Institute For Innovation In Sustainable Chemistry National Institute Of Advanced Science An

• Imura T

  National Institute Of Advanced Industrial Science And Technology (aist)

• Imura Tomohiro

  National Institute Of Advanced Industrial Science And Technology (aist)

• YOKOYAMA Shoko

  Kyoritsu College of Pharmacy

• Abe Masahiko

  Faculty Of Science And Technology Tokyo University Of Science

• SAKAI Hideki

  Institute of Colloid and Interface Science, Science University of Tokyo

• OHTA Yumiko

  Faculty of Science and Technology, Tokyo University of Science

• IMURA Tomohiro

  Faculty of Science and Technology, Tokyo University of Science

• 酒井 秀樹

  東京理科大学

• YAMAGUCHI Aritomo

  Faculty of Science and Technology, Science University of Tokyo

• ABE Masahiko

  Institute of Colloid and Interface Science

• TABOHASHI Tatsuru

  Ajinomoto Co., Inc., Amino Science Laboratories

• Yamaguchi A

  Department Of Pure And Applied Chemistry Faculty Of Science And Technology Tokyo University Of Scien

• Ohta Yumiko

  Faculty Of Science And Technology Tokyo University Of Science

• Tabohashi Tatsuru

  Ajinomoto Co. Inc. Amino Science Laboratories

• Imura Tomohiro

  Faculty Of Science And Technology Science University Of Tokyo

• Yamaguchi Aritomo

  Faculty Of Science And Technology Tokyo University Of Science

• Takeda Tadahiro

  Kyoritsu College Of Pharmacy

• Imura Tomohiro

  National Institute Of Advanced Industrial Science And Technology

• Yokoyama S

  Kyoritsu College Of Pharmacy

• Yokoyama S

  Kyushu Univ. Health And Welfare Miyazaki Jpn

• Yamaguchi Aritomo

  Department Of Pure And Applied Chemistry Faculty Of Science And Technology Tokyo University Of Scien

• Takeda Tadahiro

  Kyoritsu College Of Pharmac

• Abe M

  Faculty Of Science And Technology Science University Of Tokyo

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