Solubilization of Oil-soluble Medicines by Liposome with Deep Sea Water

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概要

• 論文の詳細を見る

• Phospholipid liposomes were prepared using deep sea water and the liposomes obtained were used to solubilize oil-soluble medicines. In addition, the dispersion stability of the liposomes was examined. Deep sea water treated with reverse osmosis membrane (RO water) gave liposomes, whereas 100% deep sea water failed to yield liposmes. Soybean lecithin liposomes solubilizing oil-soluble medicine dispersed in RO water was more stable than those dispersed in distilled water. The time needed for the liposome-medicine system to attain solubilization equilibrium was shorter in RO water than in distilled water. Moreover, a better stability was suggested for easily oxidizable vitamin A when it was solubilized in liposomes dispersed in RO water.

• 日本油化学会の論文
• 2002-02-01

著者

• Sakai Hideki

  Faculty of Science and Technology, Tokyo University of Science

• Abe Masahiko

  Faculty of Science and Technology, Tokyo University of Science

• Abe Masahiko

  Fac. Of Sci. And Technol. Tokyo Univ. Of Sci.

• Abe Masahiko

  東京理科大学 理工学部

• Abe Masahiko

  Faculty Of Science And Technology Science University Of Tokyo

• YOKOYAMA Shoko

  Kyoritsu College of Pharmacy

• Abe Masahiko

  Faculty Of Science And Technology Tokyo University Of Science

• 酒井 秀樹

  東京理科大学

• YAMAGUCHI Aritomo

  Faculty of Science and Technology, Science University of Tokyo

• KAISE Chihiro

  Faculty of Science and Technology, Science University of Tokyo

• KANEKO Teruhisa

  SHU UEMURA Co.

• Yamaguchi A

  Department Of Pure And Applied Chemistry Faculty Of Science And Technology Tokyo University Of Scien

• Yamaguchi Aritomo

  Faculty Of Science And Technology Tokyo University Of Science

• Yokoyama S

  Kyoritsu College Of Pharmacy

• Yokoyama S

  Kyushu Univ. Health And Welfare Miyazaki Jpn

• Yamaguchi Aritomo

  Department Of Pure And Applied Chemistry Faculty Of Science And Technology Tokyo University Of Scien

• Abe M

  Faculty Of Science And Technology Science University Of Tokyo

• Kaise Chihiro

  Faculty of Science and Technology, Tokyo University of Science

• SAKAI Hideki

  Faculty of Science and Technology, Science University of Tokyo

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