Synthetic Studies on Glycosphingolipids from Protostomia Phyla : Synthesis of Amphoteric Glycolipid Analogues Containing a Phosphocholine Residue from the Earthworm Pheretima hilgendorfi
スポンサーリンク
概要
- 論文の詳細を見る
Two kinds of amphoteric glycosphingolipid analogues from the earthworm Pheretima hilgendorfi were synthesized as follows : The key reaction is a coupling of a phosphocholine group at the position C-6 of 1 and 6 which was attempted using 2-chloro-2-oxo-1, 3, 2-dioxaphospholane, followed by reaction of the resulting cyclic phosphate intermediate with anhydrous trimethylamine to give 2 and 7. Subsequent debenzylation afforded target compounds (3, 8). Their ability to inhibit the histamine release in vitro was examined.
- 公益社団法人日本薬学会の論文
- 2001-11-01
著者
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SUGITA Mutsumi
Department of Chemistry, Faculty of Liberal Arts & Education, Shiga University
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GODA Yukihiro
National Institute of Health Sciences
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TAKEDA Tadahiro
Kyoritsu University of Pharmacy
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竹田 忠紘
Kyoritsu College Of Pharmacy
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竹田 忠紘
Faculty Of Pharmaceutical Sciences Nagoya City University
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Sato K
Division Of Pharmacology National Institute Of Health Sciences
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SATO Koichi
Niigata University
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Sato K
National Inst. Health Sci. Tokyo Jpn
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Sugita M
Dep. Of Chemistry Fac. Of Liberal Arts And Education Shiga Univ.
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Sugita M
Shiga Univ. Shiga Jpn
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Sugita Mutsumi
Department Of Chemistry Faculty Of Liberal Arts & Education Shiga University
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Taguchi Tomiko
Laboratory Of Plant Pathology And Genetic Engineering Faculty Of Agriculture Okayama University
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HADA Noriyasu
Kyoritsu College of Pharmacy
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Goda Yukihiro
National Inst. Of Health Sciences
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Hada N
Kyoritsu University Of Pharmacy
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SATO Koji
Kyoritsu University of Pharmacy
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SAKUSHIMA Jun-ichiro
National Institute of Health Sciences
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Takeda T
Kyoritsu University Of Pharmacy
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Takeda Tadahiro
Kyoritsu College Of Pharmacy
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Sato K
Kyoritsu University Of Pharmacy
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Takeda Tadahiro
Kyoritsu College Of Pharmac
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Sugita Mutsumi
Faculty Of Liberal Arts And Education Shiga University
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