Biological Detoxification of Waste House Wood Hydrolysate Using Ureibacillus thermosphaericus for Bioethanol Production(BIOCHEMICAL ENGINEERING)
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概要
- 論文の詳細を見る
Hydrolysates of lignocelluloses hydrolyzed by diluted sulfuric acid contain toxic compounds that inhibit ethanol production by Saccharomyces cerevisiae and the ethanologenic recombinant Escherichia coli KOll. We investigated the biological detoxification of a hydrolysate of waste house wood (WHW) by a thermophilic bacterium, Ureibacillus thermosphaericus. When the hydrolysatewas treated with this bacterium at 50℃ for 24h, the ethanol production rate by S. cerevisiae increased markedly and was comparable to that for the hydrolysate treated with an excess amount of calcium hydroxide (overliming). Chromatographic analysis of synthetic hydrolysates containing furfural or 5-hydroxymethyl furfural that are considered to be major toxic compounds in hydrolysates revealed that U. thermosphaericus degrades these compounds. In the WHW hydrolysates, however, the concentrations of these compounds were not decreased markedly by the bacterium. These results suggest that the bacterium degrades minor but more toxic compounds or phenolic compounds in the WHW hydrolysates. The combination of bacterial and overliming treatments of hydrolysates minimized significantly the decrease in ethanol production rate by E. coli KO11 as fermentation proceeded. Because the bacterium grows rapidly and does not consume sugars, our biological detoxification should be useful for bioethanol production from acid hydrolysates of lignocelluloses.
- 社団法人日本生物工学会の論文
- 2008-08-25
著者
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KATAKURA YOSHIO
Department of Biotechnology, Graduate School of Engineering, Osaka University
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SHIOYA SUTEAKI
Department of Biotechnology, Graduate School of Engineering, Osaka University
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Okuda Naoyuki
Tsukishima Kikai Co. Ltd.:department Of Biotechnology Graduate School Of Engineering Osaka Universit
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Okuda Naoyuki
Bio Business Development Group Tsukishima Kikai Co. Ltd.
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Yasuhara Kazuo
Divisions Of Toxicology National Institute Of Hygienic Sciences
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安原 加壽雄
San-ei Gen F.f.i. Inc.
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Suzuki Shingo
Department Of Bioinformatic Engineering Graduate School Of Information Science And Technology Osaka
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Katakura Yoshio
Department Of Biotechnology Graduate School Of Engineering Osaka University
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Katakura Yoshio
Department Of Agricultural Chemistry Faculty Of Agriculture The University Of Tokyo
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Ninomiya Kazuaki
Department Of Biotechnology Graduate School Of Engineering Osaka University:(present Office)institut
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Okuda Naoyuki
Sugar & Bio Technology Dept., Tsukishima Kikai Co., Ltd.
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Soneura Mayumi
Sugar & Bio Technology Dept., Tsukishima Kikai Co., Ltd.
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Suzuki Shingo
Technology Osaka University
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Kamimura Yasuhiro
Safety Evaluation Lab. Yoshitomi Pharm.
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Yoshikawa Katsunori
Department Of Bioinformatic Engineering Graduate School Of Information Science And Technology Osaka
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Kurokawa Y
Division Of Cellular & Molecular Toxicology National Institute Of Health Sciences
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Kodama Y
Biological Safety Research Center National Institute Of Health Science
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Shioya S
Department Of Biotechnology Graduate School Of Engineering Osaka University
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Shioya Suteaki
Department Of Biotechnology Graduate School Of Engineering Osaka University:(present Office)departme
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Shioya Suteaki
Technology Osaka University
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Shioya Suteaki
Department Of Biotechnology Faculty Of Engineering Osaka University
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Soneura Mayumi
Sugar & Bio Technology Dept. Tsukishima Kikai Co. Ltd.
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Kawasaki Yasushi
National Institute Of Health Sciences
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Kashida Y
Laboratory Of Veterinary Pathology Tokyo University Of Agriculture And Technology
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Kawasaki Yasushi
Div.of Toxicol. National Institute Of Health Sciences
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Katakura Yoshio
Department Of Bioinformatic Engineering Graduate School Of Information Science And Technology Osaka University
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Yasuhara Kazuo
Division Of Toxicology Biological Safety Research Center National Institute Of Hygienic Sciences
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