Gastric Emptying in Patients with Gastric Ulcers : Effects of Oral and Intramuscular Administration of Anticholinergic Drug
スポンサーリンク
概要
- 論文の詳細を見る
In our previous report on gastric emptying, we noted that delayed gastric emptying might be one of the etiological factors of gastric ulcers. Gastric emptying was measured using the acetaminophen method. The gastric emptying value was indicated as "μg/ml", the acetaminophen concentration 45 min after test meal ingestion. In this study, the effects of an anticholinergic drug on gastric emptying were investigated in gastric ulcer patients. Oral and intramuscular administrations of butropium bromide (BB) were studied. The following results were obtained; 1. Oral administration of 10 and 15mg of BB accelerated gastric emptying to a statistically significant degree (p<0.05), compared with the placebo in delayed gastric emptying cases in a dose-dependent manner (r=0.978). 2. Intramuscular administration of small doses of BB (0.25 and 0.5mg) also accelerated gastric emptying in delayed gastric emptying cases, but in general, intramuscular administration of BB (0.25〜2.0mg/person) inhibited gastric emptying in a dose dependent manner (r=-0.999). 3. Intramuscular administration of BB (0.25〜2.0mg/person) inhibited gastric emptying in a dose dependent manner in rapid gastric emptying cases (r=-0.977).
- 東海大学の論文
著者
-
Miwa Takeshi
Department Of Internal Medicine School Of Medicine Tokai University
-
Kikuchi Kazuhiro
Department Of Internal Medicine School Of Medicine Tokai University
-
Kikuchi Kazuhiro
東海大学 内科
-
HARASAWA Shigeru
Department of Internal Medicine, Tokai University School of of Medicine
-
KIKUCHI Kazuhiko
Department of Internal Medicine, School of Medicine, Tokai University
-
SENOUE Issei
Department of Internal Medicine, School of Medicine, Tokai University
-
NOMIYAMA Tetsu
Department of Internal Medicine, School of Medicine, Tokai University
-
Nomiyama Tetsu
Department Of Internal Medicine School Of Medicine Tokai University
-
Miura T
Laboratory For Immunopharmacology Of Microbial Products School Of Pharmacy Tokyo University Of Pharm
-
Miwa T
The 6th Department Of Internal Medicine School Of Medicine Tokai University
-
Mitomi Toshio
Second Department Of Surgery Tokai University School Of Medicine
-
Miwa Takeshi
The 6th Department Of Internal Medicine School Of Medicine Tokai University
-
Senoue Issei
Department Of Internal Medicine School Of Medicine Tokai University
-
Harasawa Shigeru
Department Of Internal Medicine School Of Medicine Tokai University
-
Harasawa Shigeru
Division Of Gastroenterology Ii Tokai University School Of Medicine
-
Harasawa Shigeru
Department Of Gastroenterology Ii Tokai University School Of Medicine
-
Miwa Takeshi
Department Of Internal Medicine 6 Tokai University School Of Medicine
-
Kikuchi Kazuhiko
Department of Genetic Resources II, National Institute of Agrobiological Resources
関連論文
- Introduction of Various Vietnamese Indigenous Pig Breeds and Their Conservation by Using Assisted Reproductive Techniques
- Antidiabetic activity of Cissus sicyoides in KK-Ay mice
- Effect of exogenous tetragastrin on gastric myoelectrical activity in humans
- The Role of Histamine in Ethanol-Induced Gastric Mucosal Injury in the Rat
- Abscessed Leiomyosarcoma of the Ileum
- Histamine Synthesis after Administration of Gastrin and Blockade of Acid Secretion in the Rat Stomach
- Activity and Distribution of Histidine Decarboxylase and Histamine Concentration in Rat Stomach
- A Case of Spontaneous Esophageal Rupture Treated with Conservative Therapy
- Endoscopic Manometry of the Sphincter of Oddi in Dogs Pharmacological Effects of Anticholinergic and Selective Antimuscarinic Agents
- Gastric Emptying in Patients with Gastric Ulcers : Effects of Oral and Intramuscular Administration of Anticholinergic Drug
- Epidemio-hygieological Aspects of Gastric Neoplasms in Aged Patients
- Relation between Esophagogastric Junction and Esophageal Function in Patients with Reflux Esophagitis
- Gastric Acid Secretion and Plasma Gastrin Response to Test Meal in Patients with Gastric Cancer
- Esophageal Ulceration in a Patient with Behcet's Syndrome
- A Comparative Study on Application of Nd-YAG Laser Radiation and Electrocautery in Canine Gastric Mucosa : Magnified Observations by Dissecting Microscopy and Scanning Electron Microscopy, and Histological Examinations
- Clinical Investigations in Patients with Juvenile Gastric Atrophy Compared with Senile Gastric Atrophy
- The PFD Test for Pancreatic Disease Patients
- The Coexistence of Gastric Cancer and Duodenal Ulcers
- Hematemesis and Melena : Gastritis
- Magnified Endoscopic Observations on the Healing Process of Experimental Ulcers
- Magnified Observations of the Intestinal Mucosa
- The Effects of Test Meals on the PFD Test
- Effect of Fuscoporia obliqua with exercise on blood glucose and lipid in type 2 diabetic mice
- Antidiabetic activity of Fuscoporia oblique and Samallanthus sonchifolius in genetically type 2 diabetic mice(Incentive Award, 2006)
- Esophageal Ulceration in a Patient with Behcet's Syndrome
- Hematemesis and Melena : Gastric Ulcer
- Hematemesis and Melena : Mallory-Weiss Syndrome
- Hematemesis and Melena : Endoscopic Examination
- Serum CEA Levels in Gastrointestinal Diseases
- The Therapeutics of Peptic Ulcers : Clinical Evaluation of C-Fe Therapy
- B.T. PABA Test : A New Absorption Test
- Gastrin-stimulated Gastric Acid Secretion while H_2-receptors are Blocked by an H_2-receptor Antagonist
- A Study of Fine Structures of Colorectal Mucosa and Polyps : Part I: Application of dissecting microscopy and scanning electron microscopy
- Esophageal Ulceration in a Patient with Behcet's Syndrome
- Introduction of Various Vietnamese Indigenous Pig Breeds and Their Conservation by Using Assisted Reproductive Techniques
- A Case Report of Henoch-Schoenlein Purpura Nephritis Associated with a Postbulbar Duodenal Ulcer
- 4Cで冷蔵保存された精巣上体から採取・凍結・融解した精子を用いたブタの繁殖の試み
- Failure in Antitumor Activity by Overdose of an Immunomodulating β-Glucan Preparation, Sonifilan
- Inactivation of a Particle β-Glucan by Proteins in Plasma and Serum
- Effect of Byakko-ka-ninjin-to with exercise in early stage symptom of non-insulin dependent diabetic mice
- The Suppressive Effect of Mangiferin with Exercise on Blood Lipids in Type 2 Diabetes
- Hypolipidemic activity of Mangiferin in cholesterol-fed mice
- Gastric Carcinoma with Lymphoid Stroma : Clinicopathological Studies of Four Cases
- Suppressive Activity of the Fruit of Momordica charantia with Exercise on Blood Glucose in Type 2 Diabetic Mice(Pharmacognosy)
- Antidiabetic Activity of Lyophyllum decastes in Genetically Type 2 Diabetic Mice
- Hypoglycemic Activity of the Fruit of the Momordica charantia in Type 2 Diabetic Mice
- Antidiabetic Activity of the Rhizoma of Anemarrhena asphodeloides and Active Components, Mangiferin and Its Glucoside
- Effect of Alpha-Linolenic Acid on Blood Glucose, Insulin and GLUT4 Protein Content of Type 2 Diabetic Mice
- Effect of Epinephrine of GLUT2 Protein Content in Mouse Liver
- Method for Detection of Antibody against Low Molecular Weight Antigen (Hapten) : Production and Detection of Antibody against Histamine H2 Receptor Antagonist "Famotidine"
- Peptic ulcer recurrence during maintenance therapy with H^2-receptor antagonist following first-line therapy with proton pump inhibitor
- Evaluation of Developmental Competence of In Vitro-produced Porcine Embryos Based on the Timing, Pattern and Evenness of the First Cleavage and Onset of the Second Cleavage
- Nuclear and Cytoplasmic Maturation In Vitro of Porcine Oocytes
- Effect of Procaine and Oxethazaine on Muscarinic Receptors of Parietal Cells
- Lipoma of the Stomach : A case report
- Clinical and Histological Prognostic Factors in Axillary Node-Negative Breast Cancer: Univariate and Multivariate Analysis with Relation to 5-Year Recurrence
- Prognostic Parameters in Axillary Node Negative Breast Cancer
- Serum CEA Levels in Gastrointestinal Diseases
- Clinical Evaluation of a New Type Panendoscope GIF Type P2
- Carcinoembryonic Antigen (CEA) Levels in Gastric Juice
- Dietary Corosolic Acid Ameliorates Obesity and Hepatic Steatosis in KK-Ay Mice(Pharmacognosy)
- Antidiabetic Effects of Corosolic Acid in KK-Ay Diabetic Mice(Pharmacognosy)
- A Study of 46 Cumulative Breast Cancer Autopsy Cases
- A Case of Microhepatoma Associated with Schistosomiasis Japonica Diagnosed by Enhanced Ultrasonography after Hepatic Intraarterial Injection of Carbon Dioxide Gas
- Acute Emphysematous Cholecystitis Associated with Pneumobilia : A Case Report
- Hepatic Cytokeratin Changes in Obstructive Jaundice : before and after biliary drainage
- A Recurrent Case of Spontaneous Mediastinal Emphysema
- B.T. PABA Test (Third Report) : A Pancreatic Exocrine Function Test
- B.T. PABA Test (Second Report) : A New Absorption Test
- Plasma Gastrin Response to Test Meal in Patients with Erosive Gastritis
- B.T. PABA Test; Its use with Postgastrectomy Patients
- Corosolic Acid Induces GLUT4 Translocation in Genetically Type 2 Diabetic Mice(Pharmacognosy)
- Antidiabetic Mechanism of Bakumondo-inshi
- Inhibitory Effect of Simultaneous Intraportal Administration of 5-Fluorouracil, Uracil and Degradable Starch Microspheres on Experimental Hepatic Micrometastas, is of Colon Cancer
- Two Cases of Adenolipoma of the Breast
- Isolation of Parietal Cells from Guinea-pig Gastric Mucosa by a Percoll Density Gradient
- Collagen and Collagenase in Ulcer Tissue-1. The Healing Process of Acetic Acid Ulcers in Rats
- A Mixed - Valence Mn(II,III) Complex with a 2D Structure:Crystal Structure and Magnetic Property of K[Mn_2(u - CrO_4)_2(u - OH)_2]
- Hemolytic Streptococcus Preparation OK-432; Benefical Adjuvant Therapy in Recurrent Gastric Carcinoma
- Effects of Oral Administration of Streptococcal Preparation OK-432 on Thoracic Duct Lymphocytes
- Effects of Biological Response Modifier on Thoracic Duct Lymphocytes in Recurrent Gastric Cancer Evaluation of OK-432, a Hemolytic Streptococcus Preparation
- Tracheal Agenesis : A Case Report
- The Effects of Ptoteoglycan on GALT in Rats Treated with TPN
- The Diagnosis and Treatment of Esophageal Perforations Resulting from Nonmalignant Causes
- Endoscopic Criteria for Invasive Depth of Superficial Esophageal Cancer
- Treatment of Esophageal Cancer in Patients over 80 Years Old
- Endoscopic Screening for Esophageal Cancer in 788 Patients with Head and Neck Cancers
- Effect of the Proteoglycan (PSK) on Lymphocyte Subsets in Normal Rats
- Estimation of the Functional Reserve of the Human Liver by Urinary D-Glucaric Acid Excretion after Vitamin C Administration
- Concentrations of Alpha-1-antichymotrypsin and Other Acute Phase Reactants in Patients with Gastric Cancer
- Acid Secretory Effect of Extracted Guinea-pig Gastrin on Isolated Guinea-pig Parietal Cells
- A Young Gastric Carcinoma Patient with Umbilical and Scrotal Metastasis
- The Effect of a Protein-Bound Polysaccharide on T Cell Subsets of Peripheral Venous Blood and Thoracic Duct Lymph
- Studies on Vascular Endothelial Cell Damage by Polidocanol in Relation to Concentration, Ethylene-oxide Chain Length and Exposure Time
- Clinical Experiences with Laparoscopic Colectomy
- Evaluation of Developmental Competence of In Vitro-produced Porcine Embryos Based on the Timing, Pattern and Evenness of the First Cleavage and Onset of the Second Cleavage
- 4Cで冷蔵保存された精巣上体から採取・凍結・融解した精子を用いたブタの繁殖の試み
- Development of Probiotics for Helicobacter pylori Infection
- Studies of the Medical Effectiveness of Endoscopic Treatment
- For whom do physicians examine gastric emptying? The actual situation and prospects for gastric emptying measurement