Reactions of Indole with Hydroxyl Radicals and X-Ray Crystal Structure of a Novel Indole Trimer, 14-Acetyldiindolo [2,3-a : 2', 3'-c] carbazole

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概要

• 論文の詳細を見る

• When indole reacted with titanium (III)- or iron (II)-hydrogen peroxide systems, the products varied widely, depending on the pH of the reaction solutions. Under acidic conditions, indole gave rise to oxindole, 2,3'-biindole and a novel indole trimer, diindolo-[2,3-a : 2', 3'-c] carbazole. Under neutral conditions, indole was converted to oxindole, hydroxyindoles and 3,3'-biindole. The structure of the trimer was determined by X-ray diffraction analysis of its monoacetyl derivative. A possible mechanism for the formation of the products is proposed.

• 公益社団法人日本薬学会の論文
• 1981-12-25

著者

• 金子 孝夫

  東京都老人研

• 飯高 洋一

  Faculty of Pharmaceutical Sciences, The University of Tokyo

• 松尾 光芳

  Tokyo Metropolitan Institute of Gerontology

• 飯高 洋一

  帝京大(薬)

• 松尾 光芳

  甲南大・理

• 金子 孝夫

  Tokyo Metropolitan Institute of Gerontology

• 飯高 洋一

  Faculty Of Pharmaceutical Sciences The University Of Tokyo

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