Cytotoxicities of Autoxidized Polyunsaturated Fatty Acids toward Cultured Human Umbilical Vein Endothelial Cells
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概要
- 論文の詳細を見る
Cytotoxicities of autoxidized polyunsaturated fatty acids toward human umbilical vein endothelial cells were examined. Autoxidized linoleic acid is more toxic than linoleic, autoxidized linolenic, or autoxidized arachidonic acid. Autoxidized linolenic acid is less toxic than linolenic acid. Autoxidized arachidonic acid is as toxic as linolenic or arachidonic acid. It was found that major toxic components in autoxidized linoleic acid are linoleic acid hydroperoxides, and that a major component in autoxidized arachidonic acid is (E)-4-hydroxy-2-nonenal.
- 公益社団法人日本薬学会の論文
- 1988-10-25
著者
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金子 孝夫
東京都老人研
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中野 俊一郎
東京都老人研
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松尾 光芳
Tokyo Metropolitan Institute of Gerontology
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中野 俊一郎
Tokyo Metropolitan Institute of Gerontology
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松尾 光芳
甲南大・理
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加治 和彦
Tokyo Metropolitan Institute Of Gerontology
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金子 孝夫
Tokyo Metropolitan Institute of Gerontology
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